Karagozoglu K Hakki, De Visscher Jan G, Forouzanfar Tymour, van der Meij Erik H, Jager Derk Jan
Consultant Oral and Maxillofacial Surgeon and PhD Candidate, Department of Oral and Maxillofacial Surgery and Oral Pathology, VU University Medical Center, Amsterdam, The Netherlands.
Associate Professor, Department of Oral and Maxillofacial Surgery and Oral Pathology, VU University Medical Center, Amsterdam; Department of Oral and Maxillofacial Surgery, Medical Center Leeuwarden, Leeuwarden, The Netherlands.
J Oral Maxillofac Surg. 2017 May;75(5):978-983. doi: 10.1016/j.joms.2016.09.046. Epub 2016 Oct 6.
Recent literature suggests that sialendoscopy of the major salivary glands could alleviate symptoms of Sjögren syndrome (SS) and restore salivary function. The aim of this study was to evaluate the authors' experience of sialendoscopy of the salivary glands in patients with SS.
In this retrospective case series study, the surgical data of patients with SS who had undergone sialendoscopy at the VU University Medical Center (Amsterdam, The Netherlands) from November 2014 through April 2015 were used. Outcome measurements were successful entry to the salivary gland and completion of sialendoscopy as planned. Furthermore, pre- and postoperative complications were scored. Descriptive analysis of the data was performed.
Surgical data of sialoendoscopic procedures in 26 patients with SS (24 women and 2 men; mean age, 57 yr; range, 27 to 72 yr) were analyzed. Sialendoscopy was successfully performed in 78 of 104 salivary glands (75%; 50 parotid and 28 submandibular glands) in the 26 patients. Sialendoscopy failed in 26 of the 104 sialoendoscopic procedures (25%; 2 parotid and 24 submandibular glands). In 16 salivary glands, the ductal orifice could not be identified. In 7 salivary glands, sialendoscopy could not be performed because of partial or complete stenosis of the salivary duct. In 3 salivary glands, sialendoscopy was not performed because of a ductal perforation. Three patients developed a postoperative infection.
The overall rate of complications was limited and the sialoendoscopic complications in patients with SS could be regarded as minor. Most complications were seen for sialendoscopy of the submandibular glands in this specific patient category. Careful preoperative selection of patients and salivary glands could contribute to a lower rate of complications and more predictable results.
近期文献表明，对主要唾液腺进行唾液腺内镜检查可缓解干燥综合征（SS）的症状并恢复唾液功能。本研究的目的是评估作者对SS患者进行唾液腺内镜检查的经验。
在这项回顾性病例系列研究中，使用了2014年11月至2015年4月在荷兰阿姆斯特丹VU大学医学中心接受唾液腺内镜检查的SS患者的手术数据。结果测量指标为成功进入唾液腺并按计划完成唾液腺内镜检查。此外，对术前和术后并发症进行评分。对数据进行描述性分析。
分析了26例SS患者（24例女性和2例男性；平均年龄57岁；范围27至72岁）的唾液腺内镜手术数据。26例患者的104个唾液腺中有78个成功进行了唾液腺内镜检查（75%；50个腮腺和28个下颌下腺）。104例唾液腺内镜检查中有26例失败（25%；2个腮腺和24个下颌下腺）。在16个唾液腺中，无法识别导管开口。在7个唾液腺中，由于唾液腺导管部分或完全狭窄而无法进行唾液腺内镜检查。在3个唾液腺中，由于导管穿孔未进行唾液腺内镜检查。3例患者发生术后感染。
总体并发症发生率有限，SS患者的唾液腺内镜并发症可视为轻微。在这一特定患者群体中，下颌下腺唾液腺内镜检查的并发症最为常见。术前仔细选择患者和唾液腺有助于降低并发症发生率并获得更可预测的结果。
