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计算已活时间、剩余时间还是疾病时间?年龄、接近死亡程度、发病率和处方费用。

Counting the time lived, the time left or illness? Age, proximity to death, morbidity and prescribing expenditures.

作者信息

Moore Patrick V, Bennett Kathleen, Normand Charles

机构信息

Centre for Health Policy and Management, Trinity College Dublin, Ireland; The Irish Longitudinal Study of Ageing (TILDA), Trinity College Dublin, Ireland.

Department of Pharmacology & Therapeutics, Trinity Centre for Health Sciences, St James's Hospital, Dublin, Ireland; Division of Population Health Science, Royal College of Surgeons in Ireland (RCSI), Ireland.

出版信息

Soc Sci Med. 2017 Jul;184:1-14. doi: 10.1016/j.socscimed.2017.04.038. Epub 2017 Apr 26.

DOI:10.1016/j.socscimed.2017.04.038
PMID:28482276
Abstract

The objective is to understand what really drives prescription expenditure at the end of life in order to inform future expenditure projections and service planning. To achieve this objective an empirical analysis of public medication expenditure on the older population (individuals ≥ 70 years of age) in Ireland (n = 231,780) was undertaken. A two part model is used to analysis the individual effects of age, proximity to death (PTD) and morbidity using individual patient-level data from administrative pharmacy records for 2006-2009 covering the population of community medication users. Decedents (n = 14,084) consistently use more medications and incur larger expenditures than similar survivors, especially in the last 6 months of life. The data show a positive and statistically significant impact of PTD on prescribing expenditures with minimal effect for age alone even accounting for patient morbidities. Nevertheless improved measures of morbidity are required to fully test the hypothesis that age and PTD are proxies for morbidity. The evidence presented refutes age as a driver of prescription expenditure and highlights the importance of accounting for mortality in future expenditure projections.

摘要

目的是了解在生命末期真正推动处方支出的因素,以便为未来的支出预测和服务规划提供信息。为实现这一目标,对爱尔兰老年人口(年龄≥70岁)(n = 231,780)的公共药物支出进行了实证分析。使用两部分模型,利用2006 - 2009年行政药房记录中的个体患者层面数据,分析年龄、接近死亡(PTD)和发病率对社区用药人群的个体影响。与类似的幸存者相比,死者(n = 14,084)持续使用更多药物且支出更高,尤其是在生命的最后6个月。数据显示,PTD对处方支出有正向且具有统计学意义的影响,即使考虑患者发病率,单独年龄的影响也最小。然而,需要改进发病率测量方法,以充分检验年龄和PTD是发病率替代指标这一假设。所提供的证据反驳了年龄是处方支出驱动因素的观点,并强调了在未来支出预测中考虑死亡率的重要性。

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