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低剂量类固醇治疗急性嗜酸性粒细胞性心肌炎的显著早期反应:一例报告

Dramatic and early response to low-dose steroid in the treatment of acute eosinophilic myocarditis: a case report.

作者信息

Chen Yu-Wei, Chang Yu-Cheng, Su Chieh-Shou, Chang Wei-Chun, Lee Wen-Lieng, Lai Chih-Hung

机构信息

Division of Cardiology, Department of Internal Medicine, Taichung Veterans General Hospital Chiayi Branch, Chiayi, Taiwan, Republic of China.

Department of Cardiology, Asia University Hospital, Taichung, Taiwan, Republic of China.

出版信息

BMC Cardiovasc Disord. 2017 May 8;17(1):115. doi: 10.1186/s12872-017-0547-9.

Abstract

BACKGROUND

Eosinophilic myocarditis encompasses a variety of etiologies and the prognosis varies. For patients with a hypersensitive response to medications, high-dose corticosteroids and discontinuation of culprit medications are the main treatments.

CASE PRESENTATION

We reported a young man with biopsy-proven eosinophilic myocarditis which was possibly induced by Chinese herbal medicine. His heart failure and left ventricular hypertrophy improved soon after low-dose corticosteroid.

CONCLUSION

Low-dose corticosteroid may be effective in selected patients with eosinophilic myocarditis. Early echocardiographic follow-up is mandatory for evaluation of the clinical response.

摘要

背景

嗜酸性粒细胞性心肌炎病因多样,预后各异。对于药物过敏反应患者,大剂量糖皮质激素及停用致病药物是主要治疗方法。

病例报告

我们报告了一名年轻男性,经活检证实为嗜酸性粒细胞性心肌炎,可能由中药引起。低剂量糖皮质激素治疗后,他的心力衰竭和左心室肥厚很快得到改善。

结论

低剂量糖皮质激素可能对部分嗜酸性粒细胞性心肌炎患者有效。必须进行早期超声心动图随访以评估临床反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee54/5422902/aec55a5a5096/12872_2017_547_Fig1_HTML.jpg

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