Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
Can J Cardiol. 2014 Dec;30(12):1732.e13-5. doi: 10.1016/j.cjca.2014.08.025. Epub 2014 Aug 28.
A previously healthy 48-year-old woman was evaluated for lightheadedness and chest heaviness 2 weeks after starting the herbal supplement Garcinia cambogia. She was found to be hypotensive and had an elevated serum troponin level. The patient had a progressive clinical decline, ultimately experiencing fulminant heart failure and sustained ventricular arrhythmias, which required extracorporeal membrane oxygenation support. Endomyocardial biopsy results were consistent with acute necrotizing eosinophilic myocarditis (ANEM). High-dose corticosteroids were initiated promptly and her condition rapidly improved, with almost complete cardiac recovery 1 week later. In conclusion, we have described a case of ANEM associated with the use of Garcinia cambogia extract.
一位 48 岁既往健康的女性，在开始服用草药补充剂 Garcinia cambogia 2 周后因头晕和胸部沉重感就诊。她被发现低血压和血清肌钙蛋白水平升高。患者进行性临床恶化，最终发生暴发性心力衰竭和持续性室性心律失常，需要体外膜氧合支持。心肌活检结果符合急性坏死性嗜酸性心肌炎（ANEM）。迅速开始使用大剂量皮质类固醇，她的病情迅速改善，1 周后几乎完全恢复心脏功能。总之，我们描述了 1 例与使用 Garcinia cambogia 提取物相关的 ANEM 病例。
