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服用藤黄果提取物的患者发生急性坏死性嗜酸性心肌炎,大剂量皮质类固醇治疗成功。

Acute necrotizing eosinophilic myocarditis in a patient taking Garcinia cambogia extract successfully treated with high-dose corticosteroids.

机构信息

Department of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.

出版信息

Can J Cardiol. 2014 Dec;30(12):1732.e13-5. doi: 10.1016/j.cjca.2014.08.025. Epub 2014 Aug 28.

Abstract

A previously healthy 48-year-old woman was evaluated for lightheadedness and chest heaviness 2 weeks after starting the herbal supplement Garcinia cambogia. She was found to be hypotensive and had an elevated serum troponin level. The patient had a progressive clinical decline, ultimately experiencing fulminant heart failure and sustained ventricular arrhythmias, which required extracorporeal membrane oxygenation support. Endomyocardial biopsy results were consistent with acute necrotizing eosinophilic myocarditis (ANEM). High-dose corticosteroids were initiated promptly and her condition rapidly improved, with almost complete cardiac recovery 1 week later. In conclusion, we have described a case of ANEM associated with the use of Garcinia cambogia extract.

摘要

一位 48 岁既往健康的女性,在开始服用草药补充剂 Garcinia cambogia 2 周后因头晕和胸部沉重感就诊。她被发现低血压和血清肌钙蛋白水平升高。患者进行性临床恶化,最终发生暴发性心力衰竭和持续性室性心律失常,需要体外膜氧合支持。心肌活检结果符合急性坏死性嗜酸性心肌炎(ANEM)。迅速开始使用大剂量皮质类固醇,她的病情迅速改善,1 周后几乎完全恢复心脏功能。总之,我们描述了 1 例与使用 Garcinia cambogia 提取物相关的 ANEM 病例。

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