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心理健康对有轻度创伤性脑损伤病史的退伍军人的代偿性认知训练效果无调节作用。

Mental Health Does Not Moderate Compensatory Cognitive Training Efficacy for Veterans With a History of Mild Traumatic Brain Injury.

作者信息

Pagulayan Kathleen F, O'Neil Maya, Williams Rhonda M, Turner Aaron P, Golshan Shahrokh, Roost Mai S, Laman-Maharg Benjamin, Huckans Marilyn, Storzbach Daniel, Twamley Elizabeth W

机构信息

U.S. Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA.

U.S. Department of Veterans Affairs Portland Health Care System, Portland, OR; Department of Psychiatry, Oregon Health & Science University, Portland, OR; Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR.

出版信息

Arch Phys Med Rehabil. 2017 Sep;98(9):1893-1896.e2. doi: 10.1016/j.apmr.2017.04.009. Epub 2017 May 5.

Abstract

OBJECTIVE

To examine the potential moderating effects of mental health symptoms on the efficacy of compensatory cognitive training (CCT) for Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn veterans with a history of mild traumatic brain injury (mTBI).

DESIGN

Secondary analysis of a randomized controlled trial of CCT. Posttraumatic stress disorder, depression, and substance dependence symptom severity were examined as potential moderators of CCT efficacy for subjective cognitive complaints, use of cognitive strategies, and objective neurocognitive performance.

SETTING

Three Veterans Affairs medical centers.

PARTICIPANTS

Participants included veterans with history of mTBI (N=119): 50 participated in CCT and 69 received usual care (UC).

INTERVENTION

CCT is a 10-week group-based (90 minutes per session) manualized cognitive rehabilitation intervention.

MAIN OUTCOME MEASURES

Objective (neuropsychological functioning) and subjective (self-report) cognitive functioning and use of cognitive strategies.

RESULTS

Baseline mental health symptoms did not moderate CCT efficacy: veterans who received CCT reported significantly greater improvement in cognitive difficulties and use of cognitive strategies compared with the UC group, regardless of baseline mental health symptom severity. The CCT group also demonstrated significant improvements on neuropsychological measures of attention, learning, and executive functioning compared with the UC group, regardless of baseline mental health symptom severity.

CONCLUSIONS

CCT is efficacious for improving objective cognitive functioning and compensatory strategy use for veterans with a history of mTBI, regardless of the severity of comorbid psychiatric symptoms.

摘要

目的

探讨心理健康症状对患有轻度创伤性脑损伤(mTBI)病史的持久自由行动/伊拉克自由行动/新黎明行动退伍军人进行代偿性认知训练(CCT)疗效的潜在调节作用。

设计

对CCT随机对照试验的二次分析。将创伤后应激障碍、抑郁和物质依赖症状严重程度作为CCT对主观认知主诉、认知策略使用和客观神经认知表现疗效的潜在调节因素进行研究。

地点

三个退伍军人事务医疗中心。

参与者

参与者包括有mTBI病史的退伍军人(N = 119):50人参加了CCT,69人接受常规护理(UC)。

干预措施

CCT是一项为期10周的基于小组的(每次90分钟)标准化认知康复干预。

主要观察指标

客观(神经心理功能)和主观(自我报告)认知功能以及认知策略的使用。

结果

基线心理健康症状并未调节CCT的疗效:与UC组相比,接受CCT的退伍军人在认知困难和认知策略使用方面的改善显著更大,无论基线心理健康症状严重程度如何。与UC组相比,CCT组在注意力、学习和执行功能的神经心理学测量方面也显示出显著改善,无论基线心理健康症状严重程度如何。

结论

对于有mTBI病史的退伍军人,无论共病精神症状的严重程度如何,CCT在改善客观认知功能和代偿策略使用方面均有效。

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