Das Kuntal Kanti, Bettaswamy Guru Prasad, Mehrotra Anant, Jaiswal Sushila, Jaiswal Awadhesh Kumar, Behari Sanjay
Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Asian J Neurosurg. 2017 Apr-Jun;12(2):224-227. doi: 10.4103/1793-5482.144151.
Brainstem gliomas are relatively rare in adults (<2% of all gliomas). Exophytic gliomas are focal brainstem lesions, which project into the 4 ventricle or cerebellopontine angles. These exophytic lesions are usually of low-grade histology (pilocytic astrocytoma or ganglioglioma) and have a relatively better outcome compared with brainstem gliomas as a whole. Glioblastoma is the commonest primary glial cell neoplasm and mostly occurs in the supratentorial compartment. It is rather uncommon in the brainstem and seldom has been described as having an exophytic growth pattern. Here we describe an exophytic brainstem glioblastoma arising from the medulla oblongata in a 55-year-old lady who presented with a 4 ventricular mass, and present a brief review of the literature. Till now, six cases of glioblastoma arising from the medulla oblongata have been reported. So, ours is the seventh such report. To the best of our knowledge, it also happens to be the sixth reported case of dorsally exophytic brainstem glioblastoma till date.
脑干胶质瘤在成人中相对少见(占所有胶质瘤的比例不到2%)。外生性胶质瘤是局灶性脑干病变,可突入第四脑室或桥小脑角。这些外生性病变通常组织学分级较低(毛细胞型星形细胞瘤或节细胞胶质瘤),与整体脑干胶质瘤相比预后相对较好。胶质母细胞瘤是最常见的原发性胶质细胞肿瘤,大多发生在幕上区域。它在脑干中相当罕见,很少被描述为具有外生性生长模式。在此,我们描述了一名55岁女性,其延髓出现外生性脑干胶质母细胞瘤,表现为第四脑室肿物,并对相关文献进行简要综述。到目前为止,已报道6例起源于延髓的胶质母细胞瘤。因此,我们的报告是第七例此类报告。据我们所知,这也是迄今为止第六例报道的背侧外生性脑干胶质母细胞瘤。