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Correlation between genotypes of F2 rs5896 (p.Thr165Met) polymorphism and urinary prothrombin fragment 1.

作者信息

Rungroj Nanyawan, Nettuwakul Choochai, Sawasdee Nunghathai, Sritippayawan Suchai, Yenchitsomanus Pa-Thai

机构信息

Division of Molecular Genetics, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Division of Molecular Medicine, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Urolithiasis. 2018 Aug;46(4):405-407. doi: 10.1007/s00240-017-0981-2. Epub 2017 May 8.

DOI:10.1007/s00240-017-0981-2
PMID:28484789
Abstract
摘要

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Correlation between genotypes of F2 rs5896 (p.Thr165Met) polymorphism and urinary prothrombin fragment 1.F2 rs5896（p.Thr165Met）多态性的基因型与尿凝血酶原片段1之间的相关性
Urolithiasis. 2018 Aug;46(4):405-407. doi: 10.1007/s00240-017-0981-2. Epub 2017 May 8.
2
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Whole exome sequencing reveals heparan sulfate proteoglycan 2 (HSPG2) as a potential causative gene for kidney stone disease in a Thai family.全外显子组测序揭示硫酸乙酰肝素蛋白聚糖2（HSPG2）是一个泰国家庭肾结石病的潜在致病基因。
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本文引用的文献

1
Association between human prothrombin variant (T165M) and kidney stone disease.人凝血酶原变异（T165M）与肾结石病的关联。
PLoS One. 2012;7(9):e45533. doi: 10.1371/journal.pone.0045533. Epub 2012 Sep 19.
2
Urine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers.尿液蛋白质标志物可区分含钙结石形成者的结石形成亲属和非结石形成亲属。
Am J Physiol Renal Physiol. 2006 Sep;291(3):F530-6. doi: 10.1152/ajprenal.00370.2005. Epub 2006 Apr 18.
3
Inhibition of growth and aggregation of calcium oxalate crystals in vitro--a comparison of four human proteins.
Eur J Biochem. 1998 May 1;253(3):637-44. doi: 10.1046/j.1432-1327.1998.2530637.x.
4
The urinary F1 activation peptide of human prothrombin is a potent inhibitor of calcium oxalate crystallization in undiluted human urine in vitro.人凝血酶原的尿F1激活肽在体外对未稀释的人尿中的草酸钙结晶具有强效抑制作用。
Clin Sci (Lond). 1995 Nov;89(5):533-41. doi: 10.1042/cs0890533.
5
Blood coagulation proteins and urolithiasis are linked: crystal matrix protein is the F1 activation peptide of human prothrombin.
Br J Urol. 1995 Jun;75(6):712-9. doi: 10.1111/j.1464-410x.1995.tb07377.x.
6
Inclusion of proteins into calcium oxalate crystals precipitated from human urine: a highly selective phenomenon.
Clin Chem. 1991 Sep;37(9):1589-94.