Myles Paul S, Andrews Sam, Nicholson Jonathan, Lobo Dileep N, Mythen Monty
Department of Anaesthesia and Perioperative Medicine, Alfred Hospital and Monash University, Commercial Road, Melbourne, VIC, 3004, Australia.
Department of Anaesthesia and Perioperative Medicine, Alfred Hospital, Melbourne, VIC, Australia.
World J Surg. 2017 Oct;41(10):2457-2463. doi: 10.1007/s00268-017-4055-y.
Intravenous fluid therapy is required for most surgical patients, but inappropriate regimens are commonly prescribed. The aim of this narrative review was to provide evidence-based guidance on appropriate perioperative fluid management.
We did a systematic literature search of the literature to identify relevant studies and meta-analyses to develop recommendations.
Of 275 retrieved articles, we identified 25 articles to inform this review. "Normal" saline (0.9% sodium chloride) is not physiological and can result in sodium overload and hyperchloremic acidosis. Starch colloid solutions are not recommended in surgical patients at-risk of sepsis or renal failure. Most surgical patients can have clear fluids and/or administration of carbohydrate-rich drinks up to 2 h before surgery. An intraoperative goal-directed fluid strategy may reduce postoperative complications and reduce hospital length of stay. Regular postoperative assessment of the patient's fluid status and requirements should include looking for physical signs of dehydration or hypovolemia, or fluid overload. Both hypovolemia and salt and water overload lead to adverse events, complications and prolonged hospital stay. Urine output can be an unreliable indicator of hydration status in the postoperative surgical patient. Excess fluid administration has been linked to acute kidney injury, gastrointestinal dysfunction, and cardiac and pulmonary complications.
There is good evidence supporting the avoidance of unnecessary fasting and the value of an individualized perioperative IV fluid regimen, with transition to oral fluids as soon as possible, to help patients recover from major surgery.
大多数外科手术患者都需要进行静脉输液治疗,但常用的治疗方案往往并不恰当。本叙述性综述的目的是为围手术期液体管理提供循证指导。
我们对文献进行了系统检索,以识别相关研究和荟萃分析,从而制定建议。
在检索到的275篇文章中,我们确定了25篇文章作为本综述的参考资料。“等渗”盐水(0.9%氯化钠)并非生理所需,可导致钠负荷过重和高氯性酸中毒。对于有败血症或肾衰竭风险的外科手术患者,不建议使用淀粉胶体溶液。大多数外科手术患者在手术前2小时内可饮用清亮液体和/或富含碳水化合物的饮料。术中目标导向性液体治疗策略可能会减少术后并发症并缩短住院时间。术后定期评估患者的液体状态和需求应包括寻找脱水或血容量不足或液体过载的体征。血容量不足以及盐和水过载都会导致不良事件、并发症和住院时间延长。尿量可能并不是术后外科手术患者水合状态的可靠指标。过多的液体输注与急性肾损伤、胃肠功能障碍以及心脏和肺部并发症有关。
有充分证据支持避免不必要的禁食以及个体化围手术期静脉输液方案的价值,应尽快过渡到口服补液,以帮助患者从大手术中恢复。