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1
Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.通过全外显子组测序和靶向基因测序揭示的透明细胞子宫内膜肿瘤的体细胞突变谱。
Cancer. 2017 Sep 1;123(17):3261-3268. doi: 10.1002/cncr.30745. Epub 2017 May 9.
2
Frequent Mismatch Repair Protein Deficiency in Mixed Endometrioid and Clear Cell Carcinoma of the Endometrium.子宫内膜混合性子宫内膜样癌和透明细胞癌中频繁的错配修复蛋白缺陷
Int J Gynecol Pathol. 2017 Nov;36(6):555-561. doi: 10.1097/PGP.0000000000000369.
3
Immune checkpoint inhibitors in malignancies with mismatch repair deficiency: a review of the state of the current knowledge.错配修复缺陷恶性肿瘤中的免疫检查点抑制剂：当前知识状态综述
J Investig Med. 2017 Apr;65(4):754-758. doi: 10.1136/jim-2016-000342. Epub 2017 Jan 19.
4
Regression of Chemotherapy-Resistant Polymerase ε (POLE) Ultra-Mutated and MSH6 Hyper-Mutated Endometrial Tumors with Nivolumab.纳武单抗使化疗耐药的聚合酶ε（POLE）超突变和错配修复蛋白6（MSH6）高突变子宫内膜肿瘤消退。
Clin Cancer Res. 2016 Dec 1;22(23):5682-5687. doi: 10.1158/1078-0432.CCR-16-1031. Epub 2016 Aug 2.
5
Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer.POLE 突变型子宫内膜癌中免疫激活及对帕博利珠单抗的反应
J Clin Invest. 2016 Jun 1;126(6):2334-40. doi: 10.1172/JCI84940. Epub 2016 May 9.
6
Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.食管癌对新辅助化疗的差异克隆进化
Nat Commun. 2016 Apr 5;7:11111. doi: 10.1038/ncomms11111.
7
Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1.聚合酶 e 突变和微卫星不稳定型子宫内膜癌与新抗原负荷、肿瘤浸润淋巴细胞数量以及 PD-1 和 PD-L1 表达的关联。
JAMA Oncol. 2015 Dec;1(9):1319-23. doi: 10.1001/jamaoncol.2015.2151.
8
Should endometrial clear cell carcinoma be classified as Type II endometrial carcinoma?子宫内膜透明细胞癌应归类为II型子宫内膜癌吗？
Int J Gynecol Pathol. 2015 Jan;34(1):74-84. doi: 10.1097/PGP.0000000000000111.
9
Molecular alterations in endometrial and ovarian clear cell carcinomas: clinical impacts of telomerase reverse transcriptase promoter mutation.子宫内膜和卵巢透明细胞癌中的分子改变：端粒酶逆转录酶启动子突变的临床影响。
Mod Pathol. 2015 Feb;28(2):303-11. doi: 10.1038/modpathol.2014.93. Epub 2014 Aug 1.
10
Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response.TAF1 对 p53 的磷酸化在 DNA 损伤反应中使 p53 依赖性转录失活。
Mol Cell. 2014 Jan 9;53(1):63-74. doi: 10.1016/j.molcel.2013.10.031. Epub 2013 Nov 27.

Genetic landscape of clear cell endometrial cancer and the era of precision medicine.

作者信息

Huang Gloria S, Santin Alessandro D

出版信息

Cancer. 2017 Sep 1;123(17):3216-3218. doi: 10.1002/cncr.30743. Epub 2017 May 9.

DOI:10.1002/cncr.30743
PMID:28485840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5907932/
Abstract
摘要