Woodcock Barry G, Kostev Karel, Shin Ju-Young
Int J Clin Pharmacol Ther. 2017 Jun;55(6):480-482. doi: 10.5414/CP203042.
To identify differences and similarities in benzodiazepine (BZD) prescribing patterns in elderly patients reported in two separate and independent investigations, one from Germany for the year 2014 and the other from Korea for the year 2013.
Data on patients over 65 years, who were prescribed at least one BZD, were obtained from population databases. The design and characteristics of the two studies were similar.
The use of BZDs in the elderly in Korea was several-fold higher than in Germany depending on the age stratification. Sleep disorders and depression were less common indications for BZDs in Korea. The use of long-acting BZDs in both countries was higher in patients attending general practitioners compared to specialized hospital departments and clinics. In Korea, diazepam was the most commonly used BZD in general practice. In Germany, lorazepam was the most commonly used BZD both in general practice and neuropsychiatric clinics.
CONCLUSIONS: The results of this comparison show that a reduction in the use of BZDs in the elderly in Korea may be possible and that in Germany, in some instances, these drugs may be under-used in this patient group. This cross-national comparison may help to reduce inappropriate use of BZD medication and improve prescribing in the elderly but this would have to be the subjects of a more detailed analysis. .
确定在两项独立的调查中所报告的老年患者苯二氮䓬类药物（BZD）处方模式的异同，一项来自德国的2014年调查，另一项来自韩国的2013年调查。
从人口数据库中获取65岁以上至少开具过一种BZD的患者数据。两项研究的设计和特征相似。
根据年龄分层，韩国老年人使用BZDs的比例比德国高几倍。睡眠障碍和抑郁症在韩国作为BZDs的适应证不太常见。与专科医院科室和诊所的患者相比，两国全科医生接诊的患者中长效BZDs的使用比例更高。在韩国，地西泮是全科医疗中最常用的BZD。在德国，劳拉西泮是全科医疗和神经精神科诊所中最常用的BZD。
该比较结果表明，韩国老年患者减少BZDs的使用是有可能的，而在德国，在某些情况下，这类药物在该患者群体中可能使用不足。这种跨国比较可能有助于减少BZD药物的不当使用并改善老年人的处方，但这需要更详细的分析。
