Program in Integrative Cell Signalling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
Program in Integrative Cell Signalling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Anatomy and Histology, University of Veterinary Medicine, Budapest 1078, Hungary.
Trends Cell Biol. 2017 Jun;27(6):391-392. doi: 10.1016/j.tcb.2017.04.003. Epub 2017 May 6.
Despite the well-known role of chronic mitochondrial dysfunction in the pathophysiology of the brain, the impact of acute impairment of mitochondrial activity by cannabinoids on higher brain functions is unknown. In a recent paper in Nature, Hebert-Chatelain et al. elegantly uncovered the essential role that bioenergetic processes have in the regulation of higher brain functions, such as learning and memory.
尽管慢性线粒体功能障碍在大脑的病理生理学中起着众所周知的作用，但大麻素对线粒体活性的急性损害对大脑高级功能的影响尚不清楚。在最近发表在《自然》杂志上的一篇论文中，Hebert-Chatelain 等人优雅地揭示了生物能量过程在调节学习和记忆等大脑高级功能方面的重要作用。
