Univ. Grenoble Alpes, CNRS, CEA, BIG/CBM/AFFOND, 38000, Grenoble, France.
Univ. Grenoble Alpes, CNRS, DCM UMR 5250, 38000, Grenoble, France.
Angew Chem Int Ed Engl. 2017 Jun 26;56(27):7774-7778. doi: 10.1002/anie.201702042. Epub 2017 Jun 6.
Self-assembled redox protein nanowires have been exploited as efficient electron shuttles for an oxygen-tolerant hydrogenase. An intra/inter-protein electron transfer chain has been achieved between the iron-sulfur centers of rubredoxin and the FeS cluster of [NiFe] hydrogenases. [NiFe] Hydrogenases entrapped in the intricated matrix of metalloprotein nanowires achieve a stable, mediated bioelectrocatalytic oxidation of H at low-overpotential.
自组装氧化还原蛋白纳米线已被用作耐氧氢化酶的有效电子穿梭体。在 rubredoxin 的铁硫中心和 [NiFe] 氢化酶的 FeS 簇之间实现了蛋白内/蛋白间电子转移链。包埋在金属蛋白纳米线复杂基质中的 [NiFe] 氢化酶在低过电势下实现了 H 的稳定、介体生物电化学氧化。
