Gianini Loren, Roberto Christina A, Attia Evelyn, Walsh B Timothy, Thomas Jennifer J, Eddy Kamryn T, Grilo Carlos M, Weigel Thomas, Sysko Robyn
Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 98, New York, New York.
Department of Medical Ethics & Health Policy, Perelman School of Medicine, University of Pennsylvania, Blockley Hall, Philadelphia, Pennsylvania.
Int J Eat Disord. 2017 Aug;50(8):906-916. doi: 10.1002/eat.22728. Epub 2017 May 10.
This study evaluated the DSM-5 severity specifiers for treatment-seeking groups of participants with anorexia nervosa (AN), the purging form of bulimia nervosa (BN), and binge-eating disorder (BED).
Hundred and sixty-two participants with AN, 93 participants with BN, and 343 participants with BED were diagnosed using semi-structured interviews, sub-categorized using DSM-5 severity specifiers and compared on demographic and cross-sectional clinical measures.
In AN, the number of previous hospitalizations and the duration of illness increased with severity, but there was no difference across severity groups on measures of eating pathology, depression, or measures of self-reported physical or emotional functioning. In BN, the level of eating concerns increased across the severity groups, but the groups did not differ on measures of depression, self-esteem, and most eating pathology variables. In BN, support was also found for an alternative severity classification scheme based upon number of methods of purging. In BED, levels of several measures of eating pathology and self-reported physical and emotional functioning increased across the severity groups. For BED, however, support was also found for an alternative severity classification scheme based upon overvaluation of shape and weight. Preliminary evidence was also found for a transdiagnostic severity index based upon overvaluation of shape and weight.
Overall, these data show limited support for the DSM-5 severity specifiers for BN and modest support for the DSM-5 severity specifiers for AN and BED.
本研究评估了《精神疾病诊断与统计手册》第五版(DSM - 5)中针对神经性厌食症(AN)、清除型神经性贪食症(BN)及暴饮暴食症(BED)寻求治疗的参与者群体的严重程度说明符。
对162名神经性厌食症参与者、93名神经性贪食症参与者及343名暴饮暴食症参与者进行半结构化访谈以做出诊断,使用DSM - 5严重程度说明符进行分类,并在人口统计学和横断面临床指标方面进行比较。
在神经性厌食症中,既往住院次数和病程随严重程度增加,但在进食障碍、抑郁或自我报告的身体或情绪功能指标方面,不同严重程度组之间并无差异。在神经性贪食症中,对进食问题的关注程度随严重程度组增加,但在抑郁、自尊及大多数进食障碍变量指标上,各组之间并无差异。在神经性贪食症中,还发现了基于清除方法数量的另一种严重程度分类方案的支持证据。在暴饮暴食症中,进食障碍的多项指标水平以及自我报告的身体和情绪功能随严重程度组增加。然而,对于暴饮暴食症,也发现了基于对体型和体重的过度重视的另一种严重程度分类方案的支持证据。还发现了基于对体型和体重的过度重视的跨诊断严重程度指数的初步证据。
总体而言,这些数据显示对DSM - 5中神经性贪食症严重程度说明符的支持有限,对DSM - 5中神经性厌食症和暴饮暴食症严重程度说明符的支持程度适中。