Haley Erin N, Vanderziel Alyssa M, Loree Amy M, Vagnini Kaitlyn M, Joseph-Mofford Genevieve E M, Hecht Leah M, Miller-Matero Lisa R
Henry Ford Health, Center for Health Policy and Health Services Research, Detroit, MI, United States; Michigan State University, College of Human Medicine, East Lansing, MI.
Henry Ford Health, Center for Health Policy and Health Services Research, Detroit, MI, United States; Michigan State University, College of Human Medicine, East Lansing, MI.
Eat Behav. 2025 Apr;57:101965. doi: 10.1016/j.eatbeh.2025.101965. Epub 2025 Mar 10.
Eating disorder pathology, including binge eating, is highly prevalent among women diagnosed with infertility. Binge eating has a range of consequences that may undermine fertility outcomes, yet population-specific risk and protective factors are unknown. Identifying factors associated with binge eating among this unique population may inform more sensitive and effective prevention and intervention efforts. In this cross-sectional observational study, women diagnosed with infertility completed validated self-report measures of psychiatric symptoms, eating disorder pathology, overvaluation of shape and weight (OSW), infertility distress, infertility acceptance, and trait mindfulness. Mann-Whitney U tests and two-part zero-inflated Poisson regression analyses were performed to identify associations between these factors and the presence and frequency of binge eating. In our sample (N = 188), 39.4 % endorsed recent binge eating (n = 74). These participants reported higher symptoms of anxiety (p < .001), depression (p < .001), OSW (p < .001), dietary restraint (p < .001), body mass index (<0.001), and lower mindfulness (p = .003) relative to those who denied binge eating. There were no group differences in infertility distress or acceptance. In a two-part zero-inflated Poisson regression model, higher OSW was the only factor significantly independently associated with higher odds of binge eating, whereas increased depression severity was significantly independently associated with greater binge eating frequency. Ultimately, OSW and depression may be particularly important treatment targets for women with infertility engaging in binge eating, above and beyond related psychological risk factors. Implications for future research and clinical practice are discussed.
饮食失调病理,包括暴饮暴食,在被诊断为不孕症的女性中极为普遍。暴饮暴食会产生一系列可能损害生育结果的后果,但特定人群的风险和保护因素尚不清楚。确定这一独特人群中与暴饮暴食相关的因素,可能会为更敏感、有效的预防和干预措施提供依据。在这项横断面观察性研究中,被诊断为不孕症的女性完成了关于精神症状、饮食失调病理、体型和体重过度重视(OSW)、不孕困扰、不孕接受度和特质正念的有效自我报告测量。进行了曼-惠特尼U检验和两部分零膨胀泊松回归分析,以确定这些因素与暴饮暴食的存在和频率之间的关联。在我们的样本(N = 188)中,39.4%的人认可近期有暴饮暴食行为(n = 74)。与否认暴饮暴食的人相比,这些参与者报告的焦虑症状(p <.001)、抑郁症状(p <.001)、OSW(p <.001)、饮食限制(p <.001)、体重指数(<0.001)更高,而正念更低(p =.003)。在不孕困扰或接受度方面没有组间差异。在两部分零膨胀泊松回归模型中,较高的OSW是与暴饮暴食几率较高显著独立相关的唯一因素,而抑郁严重程度增加与暴饮暴食频率较高显著独立相关。最终,对于有暴饮暴食行为的不孕女性来说,OSW和抑郁可能是特别重要的治疗靶点,超越了相关的心理风险因素。讨论了对未来研究和临床实践的启示。