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[感染性术后并发症对接受胃癌根治性切除患者长期生存的影响]

[Impact of infectious postoperative complications in the long term survival of patients gastrectomized for gastric carcinoma with curative intent].

作者信息

Salazar Abad Sarita Elena, Díaz Plasencia Juan Alberto, Yan-Quiroz Edgar Fermín, Calvanapon Prado Pamela, Marín-Córdova Norma, Churango Barreto Katherine

机构信息

Universidad Privada Antenor Orrego. Trujillo, Perú.

Universidad Privada Antenor Orrego. Trujillo, Perú; Instituto Regional de Enfermedades Neoplásicas "Luis Pinillos Ganoza". Trujillo, Perú.

出版信息

Rev Gastroenterol Peru. 2017 Jan-Mar;37(1):26-32.

Abstract

OBJECTIVE

To determine the impact of postoperative infectious complications in the long term survival of patients gastrectomized for gastric carcinoma with curative intent.

MATERIALS AND METHODS

The present cohort study evaluated a series of 79 patients diagnosed with resectable advanced gastric carcinoma with curative intent. They were grouped in: Group A (N=28): patients with postoperative infectious complications and Group B (N=51): patients who did not develop postoperative infectious complications. The study covered the years 2008-2013.

RESULTS

In group A, the survival rates at 1, 3 and 5 years was 74%, 74% and 47.6% respectively. In group B, the survival rates at 1, 3 and 5 years was 80.3%, 56% and 49.8% respectively (p=0.365). The main postoperative infectious complications not related to the surgical technique were pneumonia (20.3%), followed by urinary tract infection (3.8%). The main postoperative infectious complications related to surgical technique was sepsis (n=5), two of which were related to dehiscence esophagojejunal anastomosis, two bye gastroyeyunal fistula, another bye enterocutaneous fistula and one patient who presented abscess and necrosis peripancreatic's tissue.

CONCLUSIONS

There was no impact on survival at 5 years in patients with postoperative infectious complications after gastrectomy with curative intent. However, further studies should be carried over.

摘要

目的

确定根治性胃癌胃切除术后感染性并发症对患者长期生存的影响。

材料与方法

本队列研究评估了一系列79例诊断为可切除的晚期胃癌且有根治意图的患者。他们被分为:A组(N = 28):有术后感染性并发症的患者;B组(N = 51):未发生术后感染性并发症的患者。该研究涵盖了2008年至2013年。

结果

A组1年、3年和5年生存率分别为74%、74%和47.6%。B组1年、3年和5年生存率分别为80.3%、56%和49.8%(p = 0.365)。与手术技术无关的主要术后感染性并发症是肺炎(20.3%),其次是尿路感染(3.8%)。与手术技术相关的主要术后感染性并发症是脓毒症(n = 5),其中2例与食管空肠吻合口裂开有关,2例与胃肠瘘有关,另1例与肠皮肤瘘有关,1例患者出现胰腺周围组织脓肿和坏死。

结论

根治性胃癌胃切除术后感染性并发症患者的5年生存率没有受到影响。然而,应进行进一步的研究。

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