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糖果栓塞技术:一种用于慢性主动脉夹层假腔闭塞的新型血管内方法的技术要点及早期结果

The Candy-Plug Technique: Technical Aspects and Early Results of a New Endovascular Method for False Lumen Occlusion in Chronic Aortic Dissection.

作者信息

Rohlffs Fiona, Tsilimparis Nikolaos, Fiorucci Beatrice, Heidemann Franziska, Debus Eike Sebastian, Kölbel Tilo

机构信息

1 German Aortic Center Hamburg, Department of Vascular Medicine, University Heart Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

2 Unit of Vascular and Endovascular Surgery, Hospital S. Maria della Misericordia, University of Perugia, Italy.

出版信息

J Endovasc Ther. 2017 Aug;24(4):549-555. doi: 10.1177/1526602817709252. Epub 2017 May 11.

Abstract

PURPOSE

To describe the technical aspects and early results of the Candy-Plug technique for endovascular false lumen occlusion in chronic aortic dissection.

METHODS

A retrospective single-center study analyzing 18 consecutive patients (mean age 63 years, range 44-76; 16 men) with thoracic false lumen aneurysm in chronic aortic dissection. All patients underwent thoracic endovascular aortic repair with false lumen occlusion using the Candy-Plug technique. Primary endpoints consisted of technical success (successful deployment) and clinical success (no false lumen backflow). Secondary endpoints included 30-day mortality and morbidity as well as aortic remodeling during follow-up.

RESULTS

Technical success was 100%. Additional intraprocedural false lumen embolization at the Candy-Plug level was needed in 1 patient due to persisting false lumen backflow on the final angiogram (clinical success 94%). There were no intraprocedural complications. In the perioperative period, there were 3 minor complications: transient mild spinal cord ischemia, cervical hematoma after carotid-subclavian bypass, and a common femoral artery pseudoaneurysm. No deaths or reinterventions occurred. Complete distal false lumen occlusion was present on postoperative computed tomography in 15 patients, while 3 had minor contrast enhancement in the distal false lumen. Over a mean 9-month follow-up (range 0-26), 1 patient died due to rupture. Follow-up >6 months was available in 10 patients (mean 14.7 months, range 7-26): 7 patients showed aortic remodeling, while aneurysm size was stable in 3 patients.

CONCLUSION

The Candy-Plug technique is a feasible endovascular method to achieve false lumen occlusion and aortic remodeling in chronic aortic dissection. It is associated with low morbidity and mortality due to its minimal invasiveness.

摘要

目的

描述用于慢性主动脉夹层血管内假腔闭塞的Candy-Plug技术的技术要点和早期结果。

方法

一项回顾性单中心研究,分析18例连续的慢性主动脉夹层胸段假腔动脉瘤患者(平均年龄63岁,范围44 - 76岁;16例男性)。所有患者均采用Candy-Plug技术行胸段血管内主动脉修复术并闭塞假腔。主要终点包括技术成功(成功植入)和临床成功(无假腔逆流)。次要终点包括30天死亡率和发病率以及随访期间的主动脉重塑情况。

结果

技术成功率为100%。1例患者因最终血管造影显示假腔持续逆流,需要在Candy-Plug水平进行额外的术中假腔栓塞(临床成功率94%)。术中无并发症发生。围手术期有3例轻微并发症:短暂性轻度脊髓缺血、颈动脉 - 锁骨下动脉旁路术后颈部血肿以及股总动脉假性动脉瘤。无死亡或再次干预情况发生。15例患者术后计算机断层扫描显示远端假腔完全闭塞,3例患者远端假腔有轻微造影剂增强。平均随访9个月(范围0 - 26个月),1例患者因破裂死亡。10例患者随访时间>6个月(平均14.7个月,范围7 - 26个月):7例患者显示主动脉重塑,3例患者动脉瘤大小稳定。

结论

Candy-Plug技术是一种可行的血管内方法,可实现慢性主动脉夹层的假腔闭塞和主动脉重塑。因其微创性,其发病率和死亡率较低。

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