Inui K, Morimoto T, Komaki K, Yamamoto H, Monden Y
Second Department of Surgery, School of Medicine, University of Tokushima, Japan.
Nihon Geka Gakkai Zasshi. 1988 Oct;89(10):1722-5.
A case is reported of a patient who developed a histological unusual sarcoma in the chest wall 5.3 years after postoperative radiation therapy (5,000 rads) for breast cancer. This sarcoma showed microscopic features of malignant fibrous histiocytoma (MFH). A review of the literature disclosed 16 other cases in which MFH developed under similar circumstances. An analysis of these 16 cases and the case reported here showed that the mean radiation dose was 5,623 rads, that the time period between irradiation and the development of MFH ranged from 2 to 27 years and that wide resection offered better prognosis than chemotherapy.
报道了1例患者，该患者在乳腺癌术后接受放射治疗（5000拉德）5.3年后，胸壁出现了组织学上不寻常的肉瘤。该肉瘤具有恶性纤维组织细胞瘤（MFH）的微观特征。文献回顾发现了其他16例在类似情况下发生MFH的病例。对这16例病例和本文报道的病例进行分析显示，平均放射剂量为5623拉德，放疗与MFH发生之间的时间间隔为2至27年，广泛切除比化疗预后更好。
