雌激素受体阳性原发性乳腺鳞状细胞癌。
Estrogen receptor-positive primary squamous cell carcinoma of the breast.
作者信息
Pribish Abby M, Saglam Ozlen, Weinfurtner R Jared
机构信息
University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL, USA.
出版信息
Radiol Case Rep. 2017 Feb 4;12(2):211-214. doi: 10.1016/j.radcr.2017.01.008. eCollection 2017 Jun.
Pure primary squamous cell carcinoma of the breast (SCCB) represents around 0.1% of breast carcinomas. Diagnosis requires independence from adjacent skin without metastatic disease. SCCB is often large at presentation with nonspecific mammographic and ultrasound findings. It is typically hormone receptor negative and aggressive. Mastectomy and adjuvant chemotherapy is the most common treatment, although treatment guidelines are not well established. We present a case of pure primary SCCB detected by high risk screening mammogram and treated with breast conserving surgery, chemotherapy, and radiation. We discuss clinical, radiologic, and pathologic findings.
乳腺原发性纯鳞状细胞癌（SCCB）约占乳腺癌的0.1%。诊断需要排除邻近皮肤受累且无转移性疾病。SCCB通常在初诊时体积较大，乳房X线摄影和超声检查结果不具特异性。其通常为激素受体阴性且侵袭性强。乳房切除术和辅助化疗是最常见的治疗方法，不过治疗指南尚未完善。我们报告一例通过高危筛查乳房X线摄影发现的原发性纯SCCB病例，该病例接受了保乳手术、化疗和放疗。我们讨论了临床、放射学和病理学检查结果。
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