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一只猫的隐球菌性鼻咽息肉样肿物

Cryptococcal nasopharyngeal polypoid mass in a cat.

作者信息

Livet Véronique, Javard Romain, Alexander Kate, Girard Christiane, Dunn Marilyn

机构信息

Companion Animal Research Group, Department of Clinical Sciences, University of Montreal, Saint-Hyacinthe, QC, Canada.

出版信息

JFMS Open Rep. 2015 Jul 27;1(2):2055116915597238. doi: 10.1177/2055116915597238. eCollection 2015 Jul-Dec.

DOI:10.1177/2055116915597238
PMID:28491377
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5361995/
Abstract

CASE SUMMARY

An indoor 9-year-old castrated male domestic cat was referred with a 4 month history of increased upper airway noise. Computed tomography revealed a nasopharyngeal polypoid mass, which was removed endoscopically with basket forceps. Histopathology was compatible with a polypoid granulomatous pharyngitis with -like organisms. This was supported by a positive serum latex cryptococcal antigen agglutination test (LCAT). Minimal inflammation of the nasal tissue was noted on histopathology, with no evidence of fungus. Following endoscopic removal of the mass, the patient was treated with systemic antifungal medication (itraconazole). One year after diagnosis, the LCAT titer was negative and the cat remained free of clinical signs.

RELEVANCE AND NOVEL INFORMATION

This case report emphasizes the importance of considering species as a potential etiology in cats presented with signs of nasopharyngeal obstruction with an isolated nasopharyngeal polypoid mass, even if kept indoors.

摘要

病例摘要

一只9岁室内阉割雄性家猫因上呼吸道噪音增加4个月的病史前来就诊。计算机断层扫描显示鼻咽部有一个息肉样肿块,用篮式钳经内镜将其切除。组织病理学结果与伴有类似生物体的息肉样肉芽肿性咽炎相符。血清乳胶隐球菌抗原凝集试验(LCAT)呈阳性支持这一诊断。组织病理学检查发现鼻组织仅有轻微炎症,未发现真菌迹象。内镜下切除肿块后,对该猫使用全身性抗真菌药物(伊曲康唑)进行治疗。诊断一年后,LCAT滴度呈阴性,该猫未出现临床症状。

相关性和新信息

本病例报告强调,对于出现鼻咽部梗阻体征且仅有孤立性鼻咽息肉样肿块的猫,即使是室内饲养的猫,也应考虑将 物种作为潜在病因,这一点很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/7f92ec5c0a39/10.1177_2055116915597238-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/1b8ae8ca1a49/10.1177_2055116915597238-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/355087818f01/10.1177_2055116915597238-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/7f92ec5c0a39/10.1177_2055116915597238-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/1b8ae8ca1a49/10.1177_2055116915597238-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/355087818f01/10.1177_2055116915597238-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b27a/5361995/7f92ec5c0a39/10.1177_2055116915597238-fig3.jpg

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本文引用的文献

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Feline nasal granuloma due to Cryptoccocus gattii type VGII.猫科动物鼻腔肉芽肿由新型隐球菌 VGII 型引起。
Mycopathologia. 2013 Oct;176(3-4):303-7. doi: 10.1007/s11046-013-9686-4. Epub 2013 Aug 13.
2
Cryptococcosis in cats: ABCD guidelines on prevention and management.猫隐球菌病:预防与管理的ABCD指南
J Feline Med Surg. 2013 Jul;15(7):611-8. doi: 10.1177/1098612X13489224.
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Is there any relationship between the clinical, radiological and histopathologic findings in sinonasal polyposis?鼻-鼻窦炎鼻息肉病的临床、影像学及组织病理学表现之间是否存在关联?
Turk Patoloji Derg. 2013;29(2):127-33. doi: 10.5146/tjpath.2013.01163.
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What is your neurologic diagnosis? C gattii infection.你的神经学诊断是什么?加氏假丝酵母感染。
J Am Vet Med Assoc. 2012 Dec 1;241(11):1437-9. doi: 10.2460/javma.241.11.1437.
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Nasopharyngeal disease in cats: 2. Specific conditions and their management.猫的鼻咽部疾病:2. 特定病症及其管理。
J Feline Med Surg. 2012 May;14(5):317-26. doi: 10.1177/1098612X12444998.
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Nasopharyngeal disease in cats: 1. Diagnostic investigation.猫的鼻咽部疾病:1. 诊断性调查。
J Feline Med Surg. 2012 May;14(5):306-15. doi: 10.1177/1098612X12444997.
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Prevalence of select infectious agents in inflammatory aural and nasopharyngeal polyps from client-owned cats.客户拥有的猫的炎性耳息肉和鼻息肉中特定感染因子的患病率。
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Cryptococcosis in domestic animals in Western Australia: a retrospective study from 1995-2006.西澳大利亚家养动物隐球菌病:1995-2006 年回顾性研究。
Med Mycol. 2009;47(6):625-39. doi: 10.1080/13693780802512519.
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Clinical practice guideline: adult sinusitis.临床实践指南:成人鼻窦炎
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Long-term outcome of therapy for 59 cats and 11 dogs with cryptococcosis.59只猫和11只狗隐球菌病的长期治疗结果
Aust Vet J. 2006 Nov;84(11):384-92. doi: 10.1111/j.1751-0813.2006.00040.x.