Wolff K, Stingl G
I. Universitäts-Hautklinik Wien.
Wien Med Wochenschr. 1988 Oct 31;138(19-20):524-30.
Therapeutic strategies in the management of AIDS should aim at an inhibition of the replication and spread of HIV; the reconstitution of immune functions; an effective chemotherapy of opportunistic infections and tumors; and the prevention of new opportunistic infections. At present, these goals can be only partially achieved and where beneficial therapeutic results are obtained they are only transient in nature. Antiretroviral therapy and chemotherapy of infections have, however, resulted in some, albeit temporary, improvement of the prognosis of ARC/AIDS patients. This review summarizes the principles and results of antiretroviral treatment of the HIV infection and chemotherapy of opportunistic infections in AIDS.
艾滋病治疗策略应旨在抑制HIV的复制和传播;恢复免疫功能;有效化疗机会性感染和肿瘤;以及预防新的机会性感染。目前,这些目标只能部分实现,即使获得了有益的治疗效果,也只是暂时的。然而,抗逆转录病毒疗法和感染化疗已使艾滋病相关综合征/艾滋病患者的预后有了一些改善,尽管只是暂时的。本综述总结了HIV感染抗逆转录病毒治疗和艾滋病机会性感染化疗的原则及结果。