Magnacca Massimo, Poddighe Rosa, Del Meglio Jacopo, Lilli Alessio, Baratto Marco Tullio, Canale Maria Laura, Tessa Carlo, Salvatori Luca, Niespolo Alessandra, Vignali Claudio, Casolo Giancarlo
U.O.C. Cardiologia.
U.O.C. Diagnostica per Immagini e Radiologia Interventistica.
G Ital Cardiol (Rome). 2017 Apr;18(4):313-321. doi: 10.1714/2683.27474.
Multidetector coronary computed tomography angiography (CCTA) is increasingly used for noninvasive imaging of the coronary arteries. Radiation exposure, however, is a potential limitation to a more extensive use of this imaging modality. We aimed to demonstrate that a professional teamwork approach, including a cardiologist and a radiologist in performing CCTA, may allow to obtain best quality exams with very low radiation doses.
A total of 998 consecutive patients underwent CCTA in accordance with the most recent guidelines. The following procedures were undertaken to reduce the radiation dose: (a) preliminary cardiological evaluation to check for CCTA eligibility; (b) optimized heart rate control with beta-blockers and/or ivabradine; and (c) the use of nonstandardized computed tomography protocols and algorithms for dose reduction.
All the patients underwent a preliminary cardiological evaluation; 89% of them were pretreated with oral or intravenous beta-blockers and/or ivabradine; 806 patients (81%) were scanned by means of prospective gating, which allowed a radiation dose exposure of 161 ± 68.64 mGy; 192 patients (19%) underwent a retrospective gating protocol, with a radiation dose exposure of 1135.15 ± 485.87 mGy. In 13 patients (1%) CCTA was uninterpretable because of artifacts. Exam quality was not affected by the use of low-dose computed tomography scanning. Coronary calcium score and/or left ventricular functional analysis were never performed.
The preliminary selection and preparation of patients and optimized scanner utilization allow a substantial reduction in radiation dose for most of the patients submitted to CCTA without affecting image quality. In our experience, a team approach was necessary to allow a "low-dose learning curve" and a progressive reduction in radiation doses administered to patients by means of the prospective gating protocol.
多排螺旋CT冠状动脉血管造影(CCTA)越来越多地用于冠状动脉的无创成像。然而,辐射暴露是更广泛使用这种成像方式的一个潜在限制。我们旨在证明,一种专业的团队协作方法,即在进行CCTA时由心脏病专家和放射科医生共同参与,可能允许以非常低的辐射剂量获得高质量的检查。
总共998例连续患者按照最新指南接受了CCTA检查。采取了以下措施来降低辐射剂量:(a)进行初步心脏评估以检查CCTA的适用性;(b)使用β受体阻滞剂和/或伊伐布雷定优化心率控制;(c)使用非标准化的计算机断层扫描协议和算法来降低剂量。
所有患者均接受了初步心脏评估;其中89%接受了口服或静脉注射β受体阻滞剂和/或伊伐布雷定预处理;806例患者(81%)通过前瞻性门控进行扫描,辐射剂量为161±68.64 mGy;192例患者(19%)采用回顾性门控方案,辐射剂量为1135.15±485.87 mGy。13例患者(1%)因伪影导致CCTA无法解读。低剂量计算机断层扫描并未影响检查质量。从未进行过冠状动脉钙化评分和/或左心室功能分析。
对患者进行初步筛选和准备以及优化扫描仪的使用,可使大多数接受CCTA检查的患者的辐射剂量大幅降低,且不影响图像质量。根据我们的经验,团队协作方法对于实现“低剂量学习曲线”以及通过前瞻性门控方案逐步降低给予患者的辐射剂量是必要的。