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在使用硫唑嘌呤治疗抗合成酶综合征期间出现的发疹性黑素细胞痣。

Eruptive melanocytic nevi during azathioprine therapy for antisynthetase syndrome.

作者信息

Steinweg Stephanie A, Halvorson Christian R, Kao Grace F, Dronavalli Sridhar

机构信息

Department of Dermatology, University of Maryland Medical Center, Baltimore, USA.

出版信息

Cutis. 2017 Apr;99(4):268-270.

Abstract

Eruptive melanocytic nevi (EMN) are rare multiple benign melanocytic nevi that develop within a few months. The phenomenon has been associated with a variety of dermatologic and systemic conditions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, epidermolysis bullosa, Addison disease, human immunodeficiency virus infection, and internal malignancy, among others. It also is commonly attributed to medications, particularly immunosuppressive and chemotherapeutic agents. We report a case of EMN in a 50-year-old man undergoing azathioprine therapy for antisynthetase syndrome.

摘要

发疹性黑素细胞痣(EMN)是在数月内出现的罕见的多发性良性黑素细胞痣。这种现象与多种皮肤病和全身性疾病有关,包括史蒂文斯-约翰逊综合征、中毒性表皮坏死松解症、大疱性表皮松解症、艾迪生病、人类免疫缺陷病毒感染以及内部恶性肿瘤等。它通常也归因于药物,特别是免疫抑制剂和化疗药物。我们报告一例50岁男性患者发生EMN的病例,该患者因抗合成酶综合征正在接受硫唑嘌呤治疗。

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