Taccagni G, Cantaboni A, Dell'Antonio G, Vanzulli A, Del Maschio A
Department of Pathology, San Raffaele Hospital, University of Milan, Italy.
Acta Cytol. 1988 Nov-Dec;32(6):868-79.
The ultrastructural cytologic study of fine needle aspiration (FNA) biopsies from eight cases with mediastinal and paramediastinal lesions is reported. In these cases, electron microscopy (EM) was essential in cytologically determining the correct type of the cancer cells. The results in these cases suggest that portions of FNA biopsies from deep sites, where aspiration is difficult or requires computed tomographic scanning, should be routinely processed for plastic embedding, so that EM examination can be performed if the cells are undifferentiated, scanty or poorly preserved by light microscopic examination. The proper cytologic identification of the cell might, in fact, have a major bearing on the therapeutic choices and on the prognosis.
本文报道了8例纵隔及纵隔旁病变细针穿刺活检（FNA）的超微结构细胞学研究。在这些病例中，电子显微镜（EM）对于从细胞学上确定癌细胞的正确类型至关重要。这些病例的结果表明，对于深部部位的FNA活检样本，在穿刺困难或需要计算机断层扫描的情况下，应常规进行塑料包埋处理，以便在光镜检查发现细胞未分化、数量稀少或保存不佳时能够进行EM检查。事实上，细胞的正确细胞学鉴定可能对治疗选择和预后有重大影响。
