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采用75克2小时口服葡萄糖耐量试验及国际糖尿病和妊娠研究组(IADPSG)标准进行普遍筛查评估的妊娠期糖尿病患病率。

Prevalence of gestational diabetes mellitus evaluated by universal screening with a 75-g, 2-hour oral glucose tolerance test and IADPSG criteria.

作者信息

Karcaaltincaba Deniz, Calis Pinar, Ocal Nagehan, Ozek Aykut, Altug Inan Melis, Bayram Merih

机构信息

Department of Obstetrics and Gynecology, Gazi University Faculty of Medicine, Ankara, Turkey.

Gazi University Faculty of Medicine, Ankara, Turkey.

出版信息

Int J Gynaecol Obstet. 2017 Aug;138(2):148-151. doi: 10.1002/ijgo.12205. Epub 2017 Jun 13.

DOI:10.1002/ijgo.12205
PMID:28494099
Abstract

OBJECTIVE

To determine the prevalence of gestational diabetes mellitus (GDM) and its association with maternal age among Turkish women diagnosed by International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria.

METHODS

A cross-sectional study was conducted in 2013-2015 among non-diabetic pregnant women aged 18-49 years who were universally screened for GDM by IADPSG criteria. The percentage of women meeting each diagnostic threshold and the prevalence of GDM by age group were calculated. Linear trends were evaluated by logistic regression.

RESULTS

Among 1434 women screened, 159 (11.1%, 95% confidence interval 9.5%-12.7%) were diagnosed with GDM; eleven of these women had been diagnosed according to a fasting glucose level in the first trimester. The prevalence of GDM was 6.6% (10/151), 7.3% (37/507), 8.8% (42/479), 16.7% (45/270), and 35.2% (25/71) among women aged younger than 25, 25-29, 30-34, 35-39, and 40 years or older, respectively. GDM prevalence increased with age (P<0.001). The numbers of women diagnosed with GDM in the second trimester who exceeded one, two, and three thresholds of the 2-hour oral glucose tolerance test were 66 (44.6%), 52 (35.1%), and 30 (20.3%), respectively.

CONCLUSION

Prevalence of GDM was correlated with maternal age. Most women diagnosed in the second trimester exceeded the threshold at only one of the three timepoints.

摘要

目的

根据国际糖尿病与妊娠研究组(IADPSG)标准,确定土耳其女性中妊娠期糖尿病(GDM)的患病率及其与产妇年龄的关联。

方法

2013年至2015年对18至49岁的非糖尿病孕妇进行了一项横断面研究,这些孕妇均按照IADPSG标准进行了GDM的普遍筛查。计算了达到每个诊断阈值的女性百分比以及按年龄组划分的GDM患病率。通过逻辑回归评估线性趋势。

结果

在1434名接受筛查的女性中,159名(11.1%,95%置信区间9.5%-12.7%)被诊断为GDM;其中11名女性是根据孕早期空腹血糖水平诊断的。年龄小于25岁、25至29岁、30至34岁、35至39岁以及40岁及以上的女性中,GDM患病率分别为6.6%(10/151)、7.3%(37/507)、8.8%(42/479)、16.7%(45/270)和35.2%(25/71)。GDM患病率随年龄增加(P<0.001)。孕中期被诊断为GDM且超过2小时口服葡萄糖耐量试验一个、两个和三个阈值的女性人数分别为66名(44.6%)、52名(35.1%)和30名(20.3%)。

结论

GDM患病率与产妇年龄相关。大多数在孕中期被诊断出的女性仅在三个时间点中的一个超过阈值。

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