Li K J, Zhu M Y, Ge J
Zhongshan Ophthalmic Centre, Sun Yat-sen University, State Key Laboratory of Ophthalmology, Guangzhou 510060, China.
Zhonghua Yan Ke Za Zhi. 2017 May 11;53(5):381-385. doi: 10.3760/cma.j.issn.0412-4081.2017.05.013.
The injury and repair of retinal neurons is a common scientific problem in the occurrence, development and prognosis of neuronal visual impairment. Transplant of retinal ganglion cells (RGCs) differentiated from stem cells opens a new avenue for treatment of glaucoma and optic neuronal degenerative diseases. For the goal to explore the optimal method for RGCs replacement, this review summarizes the current information regarding the classification and application of stem cells, the growth characteristics of RGCs and the precise methods to induce RGCs, and discusses some important issues that need resolving and are related to RGCs transplantation. It is hoped that this article will provide useful theoretical basis for the research of this field. 381-385.
视网膜神经元的损伤与修复是神经元性视觉障碍发生、发展及预后过程中的一个常见科学问题。干细胞分化而来的视网膜神经节细胞（RGCs）移植为青光眼和视神经退行性疾病的治疗开辟了一条新途径。为探索RGCs替代的最佳方法这一目标，本综述总结了有关干细胞分类与应用、RGCs生长特性以及诱导RGCs的精确方法的当前信息，并讨论了一些与RGCs移植相关且需要解决的重要问题。希望本文能为该领域的研究提供有用的理论依据。381 -
