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为了评估术中红细胞输血实践随时间的变化,输血的总发生率与输注的总单位数密切相关。

For assessment of changes in intraoperative red blood cell transfusion practices over time, the pooled incidence of transfusion correlates highly with total units transfused.

机构信息

Division of Management Consulting, Department of Anesthesia, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, United States.

Department of Anesthesiology, Pain Management and Perioperative Medicine, University of Miami, Miller School of Medicine, 1400 NW 12(th) Avenue, Suite 3028, Miami, FL 33136, United States; Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, 1015 Walnut Street, Philadelphia, PA 19107, United States.

出版信息

J Clin Anesth. 2017 Jun;39:53-56. doi: 10.1016/j.jclinane.2017.03.008. Epub 2017 Mar 28.

Abstract

STUDY OBJECTIVE

Multiple studies nationwide and at single hospitals have examined changes over time in the incidence of perioperative red blood cell (RBC) transfusion. However, the cost of RBC transfusions is related to the number of RBC units transfused, not to the incidence. We evaluate whether the readily available incidence of RBC transfusion can be used as a valid surrogate measure.

DESIGN

Observational retrospective study.

SETTING

One tertiary, academic hospital.

PATIENTS

394,789 cases of 1885 procedures over N=42 quarters of the year.

INTERVENTIONS

None.

MEASUREMENT

Incidence and number of RBC units transfused intraoperatively.

MAIN RESULTS

The number of RBC units transfused per case did not follow a Poisson distribution, confirming that the number of units and incidence of transfusion are not interchangeable for analyzing decisions by case. However, with all cases of each quarter combined, the Spearman correlation was 0.98±0.01 between each quarter's incidence of RBC transfusion and mean RBC units transfused per case (P<0.0001).

CONCLUSIONS

For assessment of changes in intraoperative RBC transfusion practices over years, it is sufficient to analyze the pooled incidence of transfusion, rather than to calculate the number of units transfused.

摘要

研究目的

全国范围内和单家医院的多项研究已经考察了围手术期红细胞(RBC)输注发生率随时间的变化。然而,RBC 输血的成本与输血量有关,而不是与发生率有关。我们评估是否可以将现成的输血发生率用作有效替代指标。

设计

观察性回顾性研究。

设置

一家三级学术医院。

患者

394789 例,1885 例手术,N=42 个季度。

干预措施

无。

测量

术中 RBC 输注的发生率和单位数。

主要结果

每个病例输血量不符合泊松分布,这证实了在分析病例决策时,单位数量和输血发生率不能互换。然而,将每个季度的所有病例合并,每个季度 RBC 输血的发生率与每个病例平均输血量之间的斯皮尔曼相关系数为 0.98±0.01(P<0.0001)。

结论

对于评估多年来术中 RBC 输血实践的变化,分析汇总的输血发生率就足够了,而无需计算输血量。

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