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翻译:从模式生物到寄生植物独脚金内酯信号转导的研究进展。

Found in Translation: Applying Lessons from Model Systems to Strigolactone Signaling in Parasitic Plants.

机构信息

Cell and Systems Biology, University of Toronto and the Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON M5S 3B2, Canada.

Cell and Systems Biology, University of Toronto and the Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON M5S 3B2, Canada.

出版信息

Trends Biochem Sci. 2017 Jul;42(7):556-565. doi: 10.1016/j.tibs.2017.04.006. Epub 2017 May 9.

Abstract

Strigolactones (SLs) are small molecules that act as endogenous hormones to regulate plant development as well as exogenous cues that help parasitic plants to infect their hosts. Given that parasitic plants are experimentally challenging systems, researchers are using two approaches to understand how they respond to host-derived SLs. The first involves extrapolating information on SLs from model genetic systems to dissect their roles in parasitic plants. The second uses chemicals to probe SL signaling directly in the parasite Striga hermonthica. These approaches indicate that parasitic plants have co-opted a family of α/β hydrolases to perceive SLs. The importance of this genetic and chemical information cannot be overstated since parasitic plant infestations are major obstacles to food security in the developing world.

摘要

独脚金内酯(SLs)是一类小分子,它们作为内源性激素调节植物发育,同时作为外源性信号帮助寄生植物感染其宿主。鉴于寄生植物是具有实验挑战性的系统,研究人员正在采用两种方法来理解它们如何响应宿主来源的 SLs。第一种方法涉及从模式遗传系统推断有关 SLs 的信息,以剖析它们在寄生植物中的作用。第二种方法使用化学物质直接在寄生植物独脚金中探测 SL 信号。这些方法表明,寄生植物已经采用了一类α/β水解酶来感知 SLs。鉴于寄生植物的侵害是发展中国家粮食安全的主要障碍,这种遗传和化学信息的重要性怎么强调都不为过。

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