Tsujimura T, Ban T, Kawata M
Dept. of Clinical Pathology, Osaka Rosai Hospital.
Gan No Rinsho. 1988 Nov;34(14):2002-6.
A case of placental-site trophoblastic tumor arising in the uterus is reported. The patient, a 34-year-old female, complained of irregular menstruation. Under the diagnosis of a tumor in the uterus or the ovary, a simple total hysterectomy and right adnexectomy were performed. Histologically, the tumor cells, which were large, polygonal or rounded in shape, had infiltrated into the myometrium in clusters or singly. Immunohistochemically, most of the tumor cells were positive to hPL. Further, hCG also was present in some tumor cells, though only weakly. Because of these findings, this case was diagnosed as a placental-site trophoblastic tumor (PSTT).
报告了一例发生于子宫的胎盘部位滋养细胞肿瘤。患者为一名34岁女性，主诉月经不规律。在诊断为子宫或卵巢肿瘤后，进行了单纯全子宫切除术及右侧附件切除术。组织学检查显示，肿瘤细胞大，呈多边形或圆形，成簇或单个浸润子宫肌层。免疫组织化学检查显示，大多数肿瘤细胞对人胎盘催乳素（hPL）呈阳性反应。此外，一些肿瘤细胞中也存在人绒毛膜促性腺激素（hCG），不过反应较弱。基于这些发现，该病例被诊断为胎盘部位滋养细胞肿瘤（PSTT）。
