Heiba Sherif, Knešaurek Karin
Division of Nuclear Medicine, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA -
Division of Nuclear Medicine, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Q J Nucl Med Mol Imaging. 2017 Sep;61(3):283-291. doi: 10.23736/S1824-4785.17.02990-9. Epub 2017 May 12.
Diabetic foot infection is not only the most common cause of hospitalization among diabetic patients, but is also associated with high morbidity, mortality and major utilization of the resources. Managing diabetic patients with suspected foot infection is highly dependent on an early and accurate determination of its presence and location. Medical imaging is often used in the workup of these patients, as clinical diagnosis of osteomyelitis is often difficult, and invasive bone biopsy is infrequently used due to many limitations. In this article, we review the role and accuracy of commonly used medical imaging modalities in the evaluation of diabetic patients with suspected foot infection including osteomyelitis with particular emphasis on molecular nuclear medicine imaging. The impact of imaging on patients' management is also discussed. We finally comment on possible future directions in hybrid molecular imaging techniques.
糖尿病足感染不仅是糖尿病患者住院最常见的原因，还与高发病率、高死亡率以及大量资源利用相关。对疑似足部感染的糖尿病患者进行管理高度依赖于对感染的存在及其位置进行早期准确的判定。医学成像常用于这些患者的检查，因为骨髓炎的临床诊断往往困难，且由于诸多限制，侵入性骨活检很少使用。在本文中，我们回顾了常用医学成像模式在评估疑似足部感染（包括骨髓炎）的糖尿病患者中的作用和准确性，特别强调分子核医学成像。还讨论了成像对患者管理的影响。最后，我们对混合分子成像技术未来可能的发展方向发表评论。
