Fogelman A M, Berliner J A, Van Lenten B J, Navab M, Territo M
Department of Medicine, School of Medicine, University of California, Los Angeles 90024-1679.
Semin Thromb Hemost. 1988 Apr;14(2):206-9. doi: 10.1055/s-2007-1002778.
The interaction of lipoproteins with endothelial receptors can result in alterations in macromolecular transport, in changes in monocyte adherence to the endothelium, and in the production of monocyte chemotactic factor by the endothelium. Monocyte migration in response to such factors can further alter lipoprotein transport into the subendothelial space, and all of these factors may play a role in the development of the atherosclerotic lesion.
脂蛋白与内皮受体的相互作用可导致大分子转运的改变、单核细胞与内皮细胞黏附的变化以及内皮细胞产生单核细胞趋化因子。单核细胞对这些因子的迁移反应可进一步改变脂蛋白向内膜下间隙的转运，所有这些因素可能在动脉粥样硬化病变的发展中起作用。
