Brüggemann Petra, Szczepek Agnieszka J, Kleinjung Tobias, Ojo Michael, Mazurek Birgit
Tinnituszentrum, Charité Universitätsmedizin Berlin, Berlin.
HNO Forschungslabor, Charité Universitätsmedizin Berlin, Berlin.
Laryngorhinootologie. 2017 Sep;96(9):615-619. doi: 10.1055/s-0042-122342. Epub 2017 May 12.
Tinnitus belongs to seriously debilitating auditory conditions and is often complicated by comorbidities such as insomnia, difficulties with concentration, depression, frustration and irritability. To facilitate the grading of symptoms and the effects of therapeutic strategies, we validated a German-version Tinnitus Functional Index (TFI) in 229 subjects suffering from chronic tinnitus. Outcome validity was assessed using the Tinnitus Questionnaire (TQ, German adaptation by Goebel u. Hiller [1998]). Construct validity was assessed using the "Hamburger Allgemeine Depressionsskala" (HADS). The German TFI featured excellent internal consistency (total score Cronbach's α=0.93). Factor analysis disclosed eight TFI subscales as proposed earlier by Meikle et al. [2012]. Intercorrelations were strong both between the TFI and the TQ (r=0.83), and between the TFI and the HADS (depression r=0.49, anxiety r=0.51). The German-version TFI qualifies as a rapid and statistically robust tool for grading the impact of tinnitus on daily living and for the measurements of therapeutic effects. Regarding depressive symptomatology, sensitivity of the TFI was comparable to that of the TQ.
耳鸣属于严重使人衰弱的听觉疾病,且常伴有失眠、注意力不集中、抑郁、沮丧和易怒等合并症。为了便于症状分级和评估治疗策略的效果,我们在229名慢性耳鸣患者中验证了德文版耳鸣功能指数(TFI)。使用耳鸣问卷(TQ,由戈贝尔和希勒[1998年]进行德文改编)评估结果效度。使用“汉堡通用抑郁量表”(HADS)评估结构效度。德文版TFI具有出色的内部一致性(总分Cronbach's α = 0.93)。因子分析揭示了如米克尔等人[2012年]之前所提出的8个TFI子量表。TFI与TQ之间(r = 0.83)以及TFI与HADS之间(抑郁r = 0.49,焦虑r = 0.51)的相互关联都很强。德文版TFI堪称一种快速且具有统计学稳健性的工具,可用于对耳鸣对日常生活的影响进行分级以及测量治疗效果。关于抑郁症状,TFI的敏感性与TQ相当。