Department of Reproductive Medicine and Gynaecology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Julius Centre for Health Science and primary care, University Medical Centre Utrecht, Utrecht, the Netherlands.
Fertil Steril. 2017 Jun;107(6):1370-1379.e5. doi: 10.1016/j.fertnstert.2017.04.008. Epub 2017 May 10.
To examine construct and criterion validity of the Dutch SCREENIVF among women and men undergoing a fertility treatment.
A prospective longitudinal study nested in a randomized controlled trial.
University hospital.
PATIENT(S): Couples, 468 women and 383 men, undergoing an IVF/intracytoplasmic sperm injection (ICSI) treatment in a fertility clinic, completed the SCREENIVF.
MAIN OUTCOME MEASURE(S): Construct and criteria validity of the SCREENIVF.
RESULT(S): The comparative fit index and root mean square error of approximation for women and men show a good fit of the factor model. Across time, the sensitivity for Hospital Anxiety and Depression Scale subscale in women ranged from 61%-98%, specificity 53%-65%, predictive value of a positive test (PVP) 13%-56%, predictive value of a negative test (PVN) 70%-99%. The sensitivity scores for men ranged from 38%-100%, specificity 71%-75%, PVP 9%-27%, PVN 92%-100%. A prediction model revealed that for women 68.7% of the variance in the Hospital Anxiety and Depression Scale on time 1 and 42.5% at time 2 and 38.9% at time 3 was explained by the predictors, the sum score scales of the SCREENIVF. For men, 58.1% of the variance in the Hospital Anxiety and Depression Scale on time 1 and 46.5% at time 2 and 37.3% at time 3 was explained by the predictors, the sum score scales of the SCREENIVF.
CONCLUSION(S): The SCREENIVF has good construct validity but the concurrent validity is better than the predictive validity. SCREENIVF will be most effectively used in fertility clinics at the start of treatment and should not be used as a predictive tool.
在接受生育治疗的女性和男性中，检验荷兰 SCREENIVF 的结构效度和效标效度。
前瞻性纵向研究，嵌套于一项随机对照试验中。
大学医院。
接受生育诊所 IVF/胞浆内单精子注射（ICSI）治疗的夫妇，共 468 名女性和 383 名男性完成了 SCREENIVF 量表的填写。
SCREENIVF 的结构效度和效标效度。
女性和男性的比较拟合指数和均方根误差逼近值表明，因子模型拟合良好。在整个时间范围内，女性的医院焦虑和抑郁量表（HADS）子量表的敏感性在 61%-98%之间，特异性在 53%-65%之间，阳性预测值（PPV）在 13%-56%之间，阴性预测值（NPV）在 70%-99%之间。男性的敏感性评分范围为 38%-100%，特异性为 71%-75%，PPV 为 9%-27%，NPV 为 92%-100%。预测模型显示，女性 HADS 在第 1 次和第 4 次时间点的 68.7%和第 2 次和第 3 次时间点的 42.5%的方差可由 SCREENIVF 的总分量表来解释，男性 HADS 在第 1 次和第 2 次时间点的 58.1%和第 3 次时间点的 46.5%和 37.3%的方差可由 SCREENIVF 的总分量表来解释。
SCREENIVF 具有良好的结构效度，但同时效度优于预测效度。SCREENIVF 在治疗开始时在生育诊所中最有效，不应作为预测工具使用。
