Department of Oral & Maxillofacial-Head and Neck Surgery (Head: F. Monje-Gil), University Hospital Infanta Cristina Badajoz, Spain.
Department of Oral & Maxillofacial-Head and Neck Surgery (Head: F. Monje-Gil), University Hospital Infanta Cristina Badajoz, Spain.
J Craniomaxillofac Surg. 2017 Jul;45(7):1074-1077. doi: 10.1016/j.jcms.2017.03.019. Epub 2017 Apr 7.
The purpose of the present study was to establish the reliability of fine needle aspiration (FNA) in the diagnosis of malignant salivary gland tumors in our population and to compare our results with those of other authors.
This was a retrospective study of clinical data from 172 patients, 153 parotid tumors and 19 submandibular tumors who underwent preoperative FNA between January 2004 and December 2013. Sensitivity, specificity, positive and negative predictive values of FNA for the preoperative diagnosis of malignancy were analyzed.
For the diagnosis of malignancy an S value of 60% was obtained, which means that 40% of malignant tumors were not diagnosed by FNA. Besides an E value of 97.5% was obtained, thus indicating that FNA was negative for malignancy in up to 97.5% of all benign neoplasms. According to predictive values, we observe that FNA hit in 83.3% cases given as malignant and in 92% of cases giving as benign (PPV=83,3%; NPV=92%).
With a scarce 60% sensitivity value in our series, fine needle aspiration has evident limitations for diagnosis of malignancy in major salivary gland neoplasms. Being highly conditioned by the staff and the conditions in which it is performed, FNA is a complementary test that helps the preoperative diagnosis of the major salivary glands with radiological tests, medical history and physical examination, but that alone it is not defining of malignancy.
本研究旨在确定细针抽吸（FNA）在诊断我们人群中的恶性涎腺肿瘤的可靠性，并将我们的结果与其他作者的结果进行比较。
这是一项回顾性研究，对 2004 年 1 月至 2013 年 12 月期间接受术前 FNA 的 172 例患者（153 例腮腺肿瘤和 19 例下颌下腺肿瘤）的临床数据进行了研究。分析了 FNA 对恶性肿瘤术前诊断的敏感性、特异性、阳性和阴性预测值。
对于恶性肿瘤的诊断，获得了 60%的 S 值，这意味着 40%的恶性肿瘤未被 FNA 诊断。此外，还获得了 97.5%的 E 值，这表明 FNA 在 97.5%的所有良性肿瘤中均为阴性。根据预测值，我们观察到 FNA 在 83.3%的恶性肿瘤病例中命中，在 92%的良性肿瘤病例中命中（PPV=83，3%；NPV=92%）。
在我们的系列中，细针抽吸的敏感性值仅为 60%，因此在大涎腺肿瘤的恶性肿瘤诊断中存在明显的局限性。由于受到工作人员和操作条件的高度影响，FNA 是一种辅助性检查，可以帮助影像学检查、病史和体格检查对大涎腺进行术前诊断，但单凭它不能确定恶性肿瘤。
