Meyer B U, Benecke R, Dressler D, Haug B, Conrad B
Abteilung für Klinische Neurophysiologie der Universität Göttingen.
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1988 Dec;19(4):234-40.
Two different approaches of determining central motor conduction times were investigated. Both methods were based on calculations of latency differences of muscle compound action potentials. First, using multilocal stimulation of the descending motor system at different levels (motor cortex, motor tracts at spinal level, motor roots) and recording from one reference muscle (Figs. 1 and 2). Second, using unilocal stimulation over the motor cortex and recording from a number of paravertebral muscles at levels from C7 to L5 (Figs. 3 and 4). With multilocal stimulation of the motor pathways, muscle response potentials are observed which differ in amplitude, duration and configuration depending on the site of stimulation (Figs. 1 and 2). This finding points to the incongruency of excited fibres within the descending motor pathways. The causes underlying this phenomenon and the resulting limitations for determining central motor conduction times are discussed. The new approach using recordings of cortically evoked responses on different levels in paravertebral muscles does not suffer from the methodical limitations of the multilocal stimulation and may be of higher clinical validity for the localization of circumscript spinal processes.
研究了两种不同的确定中枢运动传导时间的方法。这两种方法均基于肌肉复合动作电位潜伏期差异的计算。第一种方法是在不同水平(运动皮层、脊髓水平的运动束、运动神经根)对下行运动系统进行多点刺激,并从一块参考肌肉进行记录(图1和图2)。第二种方法是在运动皮层进行单点刺激,并从C7至L5水平的多个椎旁肌进行记录(图3和图4)。通过对运动通路进行多点刺激,可以观察到肌肉反应电位,其幅度、持续时间和形态会因刺激部位的不同而有所差异(图1和图2)。这一发现表明下行运动通路内兴奋纤维的不一致性。本文讨论了这一现象背后的原因以及由此对确定中枢运动传导时间造成的限制。在椎旁肌不同水平记录皮层诱发反应的新方法不存在多点刺激的方法学局限性,对于局限性脊髓病变的定位可能具有更高的临床有效性。