非惰性与惰性肥大细胞增多症的影像学特征及分布差异：一家机构29例患者的经验
Differences in the imaging features and distribution of non-indolent and indolent mastocytosis: a single institution experience of 29 patients.
作者信息
Epelboym Yan, Keraliya Abhishek R, Tirumani Sree Harsha, Hornick Jason L, Ramaiya Nikhil H, Shinagare Atul B
机构信息
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States; Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, United States.
出版信息
Clin Imaging. 2017 Jul-Aug;44:111-116. doi: 10.1016/j.clinimag.2017.05.003. Epub 2017 May 6.
PURPOSE
Compare imaging features of indolent and non-indolent mastocytosis.
METHODS
For 29 patients, imaging features, imaging indications, and distribution of indolent and non-indolent mastocytosis subtypes were analyzed.
RESULTS
16/29 (55%) patients had three distinct patterns of osseous abnormality, not significantly differing between cohorts. Non-indolent disease was more likely to present with hepatomegaly (p=0.0004), splenomegaly (p=0.0097), and lymphadenopathy (p=0.0079). CT, was the most common initial imaging modality, ordered to stage disease in 20 of 29 patients (69%).
CONCLUSION
Understanding patterns of involvement of indolent and nonindolent mastocytosis across modalities could assist radiologists in evaluating mastocytosis.
目的
比较惰性和非惰性肥大细胞增多症的影像学特征。
方法
对29例患者的影像学特征、影像学检查指征以及惰性和非惰性肥大细胞增多症亚型的分布进行分析。
结果
29例患者中有16例（55%）出现三种不同的骨质异常模式，各队列之间无显著差异。非惰性疾病更易出现肝肿大（p=0.0004）、脾肿大（p=0.0097）和淋巴结病（p=0.0079）。CT是最常用的初始影像学检查方式，29例患者中有20例（69%）接受CT检查以进行疾病分期。
结论
了解惰性和非惰性肥大细胞增多症在不同检查方式下的受累模式，有助于放射科医生评估肥大细胞增多症。
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