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[系统性肥大细胞增多症:现代影像学方法在该疾病诊断中的意义]

[Systemic mastocytosis: significance of contemporary methods of imaging in diagnosis of this disease].

作者信息

Błaszczyk B, Brzezińska-Błaszczyk E

机构信息

Katedry Diagnostyki Obrazowej, Wojskowej Akademii Medycznej, Lodzi.

出版信息

Przegl Lek. 1994;51(6):249-54.

PMID:7938660
Abstract

Mastocytosis is a rare disease characterized by increase in mast cell numbers. The most frequent organ identified as the site of increased numbers of mast cells is the skin. However, uncontrolled growth of mast cells may occur in many other organs and tissues; this disease is called systemic mastocytosis. Nowadays there are four categories of mast cell disease: 1) indolent mastocytosis, 2) mastocytosis with a hematologic disorder, 3) aggressive mastocytosis, and 4) mast cell leukemia. Although the diagnosis of systemic mastocytosis rests finally on identification of mast cells by histopathological examination of the involved tissues, radiological studies may suggest more decisive tests. In this paper the authors discuss usefulness of different methods of radiological imaging in the diagnostics of mastocytosis.

摘要

肥大细胞增多症是一种以肥大细胞数量增加为特征的罕见疾病。最常被确定为肥大细胞数量增加部位的器官是皮肤。然而,肥大细胞的不受控制生长可能发生在许多其他器官和组织中;这种疾病被称为系统性肥大细胞增多症。如今有四类肥大细胞疾病:1)惰性肥大细胞增多症,2)伴有血液系统疾病的肥大细胞增多症,3)侵袭性肥大细胞增多症,以及4)肥大细胞白血病。尽管系统性肥大细胞增多症的诊断最终依赖于通过对受累组织进行组织病理学检查来识别肥大细胞,但放射学研究可能提示更具决定性的检查。在本文中,作者讨论了不同放射学成像方法在肥大细胞增多症诊断中的实用性。

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