Mousa Hayat, Hassan Maheen
University of California, San Diego, 3020 Children's Way, MOB 211, MC 5030, San Diego, CA 92123, USA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rady Children's Hospital, 7960 Birmingham Way, Room 2110, MC 5030, San Diego, CA 92123, USA.
University of California, San Diego, 3020 Children's Way, MOB 211, MC 5030, San Diego, CA 92123, USA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rady Children's Hospital, 7960 Birmingham Way, Room 2110, MC 5030, San Diego, CA 92123, USA.
Pediatr Clin North Am. 2017 Jun;64(3):487-505. doi: 10.1016/j.pcl.2017.01.003.
Gastroesophageal reflux (GER) is a normal physiologic process. It is important to distinguish GER from GER disease (GERD) since GER does not require treatment. Although a diagnosis of GERD can largely be based on history and physical alone, endoscopy and pH impedance studies can help make the diagnosis when there in atypical presentation. In children and adolescents, lifestyle changes and acid suppression are first-line treatments for GERD. In infants, acid suppression is not effective, but a trial of hydrolyzed formula can be considered, as milk protein sensitivity can be difficult to differentiate from GER symptoms.
胃食管反流(GER)是一种正常的生理过程。区分GER和胃食管反流病(GERD)很重要,因为GER不需要治疗。虽然GERD的诊断很大程度上可以仅基于病史和体格检查,但当出现非典型表现时,内镜检查和pH阻抗研究有助于做出诊断。在儿童和青少年中,生活方式改变和抑酸是GERD的一线治疗方法。在婴儿中,抑酸无效,但可以考虑试用水解配方奶粉,因为牛奶蛋白敏感性可能难以与GER症状区分开来。