Suppr超能文献

胃食管反流病

Gastroesophageal Reflux Disease.

作者信息

Mousa Hayat, Hassan Maheen

机构信息

University of California, San Diego, 3020 Children's Way, MOB 211, MC 5030, San Diego, CA 92123, USA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rady Children's Hospital, 7960 Birmingham Way, Room 2110, MC 5030, San Diego, CA 92123, USA.

University of California, San Diego, 3020 Children's Way, MOB 211, MC 5030, San Diego, CA 92123, USA; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Rady Children's Hospital, 7960 Birmingham Way, Room 2110, MC 5030, San Diego, CA 92123, USA.

出版信息

Pediatr Clin North Am. 2017 Jun;64(3):487-505. doi: 10.1016/j.pcl.2017.01.003.

Abstract

Gastroesophageal reflux (GER) is a normal physiologic process. It is important to distinguish GER from GER disease (GERD) since GER does not require treatment. Although a diagnosis of GERD can largely be based on history and physical alone, endoscopy and pH impedance studies can help make the diagnosis when there in atypical presentation. In children and adolescents, lifestyle changes and acid suppression are first-line treatments for GERD. In infants, acid suppression is not effective, but a trial of hydrolyzed formula can be considered, as milk protein sensitivity can be difficult to differentiate from GER symptoms.

摘要

胃食管反流(GER)是一种正常的生理过程。区分GER和胃食管反流病(GERD)很重要,因为GER不需要治疗。虽然GERD的诊断很大程度上可以仅基于病史和体格检查,但当出现非典型表现时,内镜检查和pH阻抗研究有助于做出诊断。在儿童和青少年中,生活方式改变和抑酸是GERD的一线治疗方法。在婴儿中,抑酸无效,但可以考虑试用水解配方奶粉,因为牛奶蛋白敏感性可能难以与GER症状区分开来。

相似文献

1
Gastroesophageal Reflux Disease.
Pediatr Clin North Am. 2017 Jun;64(3):487-505. doi: 10.1016/j.pcl.2017.01.003.
2
Gastroesophageal reflux: management guidance for the pediatrician.
Pediatrics. 2013 May;131(5):e1684-95. doi: 10.1542/peds.2013-0421. Epub 2013 Apr 29.
3
Diagnostic work-up of GERD.
Gastrointest Endosc Clin N Am. 2014 Oct;24(4):655-66. doi: 10.1016/j.giec.2014.07.002. Epub 2014 Jul 30.
4
AGA Clinical Practice Update on the Diagnosis and Management of Extraesophageal Gastroesophageal Reflux Disease: Expert Review.
Clin Gastroenterol Hepatol. 2023 Jun;21(6):1414-1421.e3. doi: 10.1016/j.cgh.2023.01.040. Epub 2023 Apr 14.
5
The Correlation between Endoscopic Reflux Esophagitis and Combined Multichannel Intraluminal Impedance-pH Monitoring in Children.
Pediatr Neonatol. 2016 Oct;57(5):385-389. doi: 10.1016/j.pedneo.2015.09.008. Epub 2015 Dec 23.
7
Gastroesophageal reflux disease (GERD) in children.
Paediatr Int Child Health. 2019 Feb;39(1):7-12. doi: 10.1080/20469047.2018.1489649. Epub 2018 Aug 6.
8
Gastroesophageal reflux disease in infants: how much is predictable with questionnaires, pH-metry, endoscopy and histology?
J Pediatr Gastroenterol Nutr. 2005 Feb;40(2):210-5. doi: 10.1097/00005176-200502000-00024.
9
Discerning differences: gastroesophageal reflux and gastroesophageal reflux disease in infants.
Adv Neonatal Care. 2004 Aug;4(4):235-47. doi: 10.1016/j.adnc.2004.05.006.

引用本文的文献

1
Childhood gastroesophageal reflux disease: A comprehensive review of disease, diagnosis, and therapeutic management.
World J Clin Pediatr. 2025 Jun 9;14(2):101175. doi: 10.5409/wjcp.v14.i2.101175.
2
Analysis of multichannel intraluminal impedance and pH monitoring values in children with cerebral palsy: A comparative multicenter study.
J Pediatr Gastroenterol Nutr. 2025 Jul;81(1):125-130. doi: 10.1002/jpn3.70058. Epub 2025 May 6.
3
The Role of Paramedics in Diagnosing Sandifer's Syndrome.
Healthcare (Basel). 2025 Apr 11;13(8):883. doi: 10.3390/healthcare13080883.
8
Critical appraisal of how COVID-19 infection and imposed lockdowns have impacted gastroesophageal reflux: A review.
Medicine (Baltimore). 2024 May 10;103(19):e38074. doi: 10.1097/MD.0000000000038074.
9
Pediatric nutritional surgery and its implications: results from a unicentric retrospective analysis.
Pediatr Surg Int. 2024 May 2;40(1):116. doi: 10.1007/s00383-024-05700-5.
10
Oesophageal stricture in a cat with true pleuroperitoneal hernia.
Vet Med Sci. 2024 Mar;10(2):e1392. doi: 10.1002/vms3.1392.

本文引用的文献

1
Treatment Challenges in the Management of Gastroparesis-Related GERD.
Gastroenterol Hepatol (N Y). 2009 Oct;5(10 Suppl 18):4-16.
3
Salivary Pepsin Lacks Sensitivity as a Diagnostic Tool to Evaluate Extraesophageal Reflux Disease.
J Pediatr. 2016 Oct;177:53-58. doi: 10.1016/j.jpeds.2016.06.033. Epub 2016 Jul 21.
4
Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children.
Pediatr Gastroenterol Hepatol Nutr. 2016 Mar;19(1):12-9. doi: 10.5223/pghn.2016.19.1.12. Epub 2016 Mar 22.
5
Biomarkers of Reflux Disease.
Clin Gastroenterol Hepatol. 2016 Jun;14(6):790-797. doi: 10.1016/j.cgh.2015.09.014. Epub 2015 Sep 25.
6
Temporal Association Between Reflux-like Behaviors and Gastroesophageal Reflux in Preterm and Term Infants.
J Pediatr Gastroenterol Nutr. 2016 Apr;62(4):556-61. doi: 10.1097/MPG.0000000000000968.
7
The Role of Sleep in the Modulation of Gastroesophageal Reflux and Symptoms in NICU Neonates.
Pediatr Neurol. 2015 Sep;53(3):226-32. doi: 10.1016/j.pediatrneurol.2015.05.012. Epub 2015 May 29.
8
Pathophysiology of gastroesophageal reflux disease: new understanding in a new era.
Neurogastroenterol Motil. 2015 Sep;27(9):1202-13. doi: 10.1111/nmo.12611. Epub 2015 Jun 5.
9
Use of proton pump inhibitors is associated with fractures in young adults: a population-based study.
Osteoporos Int. 2015 Oct;26(10):2501-7. doi: 10.1007/s00198-015-3168-0. Epub 2015 May 19.
10
Physiology and pathogenesis of gastroesophageal reflux disease.
Surg Clin North Am. 2015 Jun;95(3):515-25. doi: 10.1016/j.suc.2015.02.006. Epub 2015 Mar 24.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验