Fukui Toshiro, Takahashi Mio, Okazaki Takashi, Tomiyama Takashi, Fukata Norimasa, Ando Yugo, Okazaki Kazuichi
The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Japan.
Intern Med. 2017;56(10):1157-1161. doi: 10.2169/internalmedicine.56.8041. Epub 2017 May 15.
A 24-year-old woman was transferred to our hospital under suspicion of an exacerbation of her known ulcerative colitis. Colonoscopy revealed an edematous swelling and multifocal discharge of pus throughout the descending colon, concurrent with active ulcerative colitis findings in the rectum and sigmoid colon. Computed tomography showed a thickened wall and multifocal abscesses within the wall of the descending colon. Two weeks after starting antimicrobial therapy, she was discharged home. This is the first case report of multifocal colonic wall abscesses. In order not to increase the risk of serious infection associated with anti-TNF-α therapy, proper qualification and strict monitoring are essential.
一名24岁女性因已知溃疡性结肠炎病情加重被转诊至我院。结肠镜检查显示降结肠全程水肿肿胀且有多处脓性分泌物，同时直肠和乙状结肠存在活动性溃疡性结肠炎表现。计算机断层扫描显示降结肠肠壁增厚且壁内有多处脓肿。开始抗菌治疗两周后，她出院回家。这是多灶性结肠壁脓肿的首例病例报告。为避免增加与抗TNF-α治疗相关的严重感染风险，恰当的评估和严格的监测至关重要。
