Yoshino Naoyuki, Hirata Tomomi, Takeuchi Chie, Usuda Jitsuo, Hosone Masaru
Department of Thoracic Surgery, Nippon Medical School Tama Nagayama Hospital.
Department of Thoracic Surgery, Nippon Medical School.
J Nippon Med Sch. 2017;84(2):87-89. doi: 10.1272/jnms.84.87.
Herein, we describe our experience in treating a case of primary pulmonary mucosa-associated lymphoid tissue lymphoma detected as a nodular opacity. A 79-year-old man was referred to our hospital. Computed tomography showed a nodular opacity measuring 20 mm in diameter with regular margins in segment 5 of the right middle lobe of the lung. Although the bronchoscopic brush cytology result was class III, the patient was tentatively diagnosed with suspected mucosa-associated lymphoid tissue lymphoma. A thoracoscopic right middle lobectomy was performed. The pathological findings showed nodular proliferation of small to medium-sized, mature-appearing atypical lymphoid cells, lymphoepithelial lesions, and vague follicles suggesting follicular colonization in some areas. The patient was diagnosed with low-grade small B-cell lymphoma and mucosa-associated lymphoid tissue lymphoma. He has remained well to date, 23 months after surgery, without evidence of recurrence.
在此，我们描述了我们治疗一例以结节状不透明影发现的原发性肺黏膜相关淋巴组织淋巴瘤的经验。一名79岁男性被转诊至我院。计算机断层扫描显示右肺中叶5段有一个直径20 mm、边缘规则的结节状不透明影。尽管支气管镜刷检细胞学结果为Ⅲ级，但该患者被初步诊断为疑似黏膜相关淋巴组织淋巴瘤。实施了胸腔镜下右肺中叶切除术。病理结果显示，小至中等大小、外观成熟的非典型淋巴细胞呈结节状增生，存在淋巴上皮病变，部分区域可见模糊的滤泡，提示滤泡植入。该患者被诊断为低级别小B细胞淋巴瘤和黏膜相关淋巴组织淋巴瘤。术后23个月至今，他情况良好，无复发迹象。
