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[一名患有葡萄糖-6-磷酸脱氢酶缺乏症的三岁儿童摄入蚕豆后发生蚕豆病]

[Favism after ingestion of fava beans in a three-year-old child with glucose-6-phosphate dehydrogenase deficiency].

作者信息

Sköld Margrethe Bordado, Svendsen Rikke Pilsgaard, Pedersen Ellen Bøtker

出版信息

Ugeskr Laeger. 2017 May 15;179(20).

Abstract

A three-year-old Syrian boy was hospitalized with symptoms of acute haemolytic anaemia after ingestion of fava beans. He was stabilized by blood transfusion, and genetic examination revealed glucose-6-phosphate dehydrogenase (G6PD) deficiency. Oxidative stress, e.g. ingestion of fava beans, can induce acute haemolytic anaemia in affected individuals. Approximately 400 million people worldwide suffer from G6PD deficiency. The prevalence is high in African, Mediterranean and Middle East countries. Due to increased immigration, we might expect the condition to occur more often in Danish healthcare.

摘要

一名三岁的叙利亚男孩在食用蚕豆后因急性溶血性贫血症状入院治疗。通过输血病情得到稳定,基因检测显示其缺乏葡萄糖-6-磷酸脱氢酶(G6PD)。氧化应激,如食用蚕豆,可在受影响个体中诱发急性溶血性贫血。全球约有4亿人患有G6PD缺乏症。在非洲、地中海和中东国家,该病的患病率很高。由于移民增加,我们预计在丹麦的医疗保健中这种情况会更频繁地出现。

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