Yildiz Hulya Kurtul, Ekin Elif Evrim
J Back Musculoskelet Rehabil. 2017 Sep 22;30(5):1061-1067. doi: 10.3233/BMR-169666.
Lumbar lordosis is required for bipedalism.
To investigate age-related changes in lumbar lordosis and to clarify the relationships between lumbar lordosis and vertebral wedging and disc degeneration.
A total of 300 women were included in this retrospective study, 50 in each of six age groups (20-, 30-, 40-, 50-, 60- and 70-year-olds). Patients with vertebral collapse, instable fracture or disc sequestration were excluded. In each patient, lumbar lordosis angle, posterior vertebral wedging, L5-S1 intervertebral disc angle, L5/L1 vertebral height ratio and L5-S1 intervertebral disc/L1-L2 intervertebral disc height ratio were examined. Significance level was set at p< 0.05 and two-sided tests were used.
Significant differences were found in lumbar lordosis according to age group (p< 0.001). Lumbar lordosis correlated most strongly with L4 posterior vertebral wedging, L5 posterior vertebral wedging and L5-S1 intervertebral disc angle, in that order (r= 0.50, r= 0.40, r= 0.32, respectively; p< 0.001).
In this cohort, strong spinal structure was maintained during physiological aging from 20 to 40 years of age; lumbar lordosis increased by 50 years of age. Increased lordosis correlated with increased posterior vertebral wedging and loss of posterior disc height.
腰椎前凸是两足行走所必需的。
研究腰椎前凸的年龄相关变化，并阐明腰椎前凸与椎体楔形变和椎间盘退变之间的关系。
本回顾性研究共纳入300名女性，分为六个年龄组（20岁、30岁、40岁、50岁、60岁和70岁），每组50人。排除椎体塌陷、不稳定骨折或椎间盘游离的患者。对每位患者检查腰椎前凸角、椎体后缘楔形变、L5-S1椎间盘角度、L5/L1椎体高度比以及L5-S1椎间盘/L1-L2椎间盘高度比。显著性水平设定为p<0.05，并采用双侧检验。
根据年龄组，腰椎前凸存在显著差异（p<0.001）。腰椎前凸与L4椎体后缘楔形变、L5椎体后缘楔形变和L5-S1椎间盘角度的相关性最强，顺序依次为（r分别为0.50、0.40、0.32；p<0.001）。
在该队列中，20至40岁生理衰老过程中脊柱结构保持稳固；50岁时腰椎前凸增加。腰椎前凸增加与椎体后缘楔形变增加和椎间盘后缘高度丢失相关。
