Suzuki Takashi, Takao Hiroyuki, Fujimura Soichiro, Dahmani Chihebeddine, Ishibashi Toshihiro, Mamori Hiroya, Fukushima Naoya, Murayama Yuichi, Yamamoto Makoto
Graduate School of Mechanical Engineering, Tokyo University of Science, Tokyo 125-8585, Japan.
Division of Endovascular Neurosurgery, Department of Neurosurgery, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Technol Health Care. 2017 Aug 9;25(4):611-623. doi: 10.3233/THC-160535.
Although flow diversion is a promising procedure for aneurysm treatment, the safety and efficacy of this strategy have not been sufficiently characterized. Both mechanical properties and flow reduction effects are important factors in the design of an optimal stent.
We aimed to clarify the contributions of strut size and pitch to the mechanical properties (radial stiffness and longitudinal flexibility) and geometric characteristics (porosity and pore density) related to flow reduction effects.
Crimping and bending behaviors of the stents were simulated with the finite element method. The relationships between the mechanical properties and geometric characteristics were investigated by changing the strut size and pitch.
Within the porosity range of 79-82%, the radial stiffness of the stent was similarly influenced by either the strut size or pitch. However, the longitudinal flexibility tended to be influenced more by strut size than by pitch.
Adjusting the strut size rather than the pitch can change the mechanical properties while minimizing the change in porosity or pore density related to flow reduction effects.
尽管血流导向是一种很有前景的动脉瘤治疗方法，但该策略的安全性和有效性尚未得到充分阐明。机械性能和血流减少效果都是优化支架设计的重要因素。
我们旨在阐明支杆尺寸和节距对与血流减少效果相关的机械性能（径向刚度和纵向柔韧性）和几何特性（孔隙率和孔隙密度）的影响。
采用有限元方法模拟支架的压握和弯曲行为。通过改变支杆尺寸和节距研究机械性能与几何特性之间的关系。
在孔隙率为79%-82%的范围内，支架的径向刚度受支杆尺寸或节距的影响相似。然而，纵向柔韧性受支杆尺寸的影响往往大于节距。
调整支杆尺寸而非节距可以改变机械性能，同时使与血流减少效果相关的孔隙率或孔隙密度变化最小化。
