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使用原始的Beers标准及其西班牙文改编版识别65岁以上患者中潜在不适当的处方

[Identifying potentially inappropriate prescriptions in patients over 65 years-old using original Beers criteria and their Spanish adaptation].

作者信息

Pastor Cano Josep, Aranda García Ana, Gascón Cánovas Juan José, Sánchez Ruiz José Francisco, Rausell Rausell Víctor José, Tobaruela Soto Mariana

机构信息

Servicio de Gestión Farmacéutica, Dirección General Asistencia Sanitaria, Servicio Murciano de Salud, Murcia, España.

Servicio de Gestión Farmacéutica, Dirección General Asistencia Sanitaria, Servicio Murciano de Salud, Murcia, España.

出版信息

Aten Primaria. 2018 Feb;50(2):106-113. doi: 10.1016/j.aprim.2017.02.010. Epub 2017 May 13.

DOI:10.1016/j.aprim.2017.02.010
PMID:28506569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6836936/
Abstract

OBJECTIVE

To compare the detection of potentially inappropriate medication (PIM) using the original Beers criteria, a global reference for evaluating prescriptions in the elderly, and their Spanish version.

DESIGN

Retrospective observational study LOCATION: A Primary Care area in the province of Murcia, Spain.

PARTICIPANTS

A total of 7,856 subjects aged 65 and over, with at least one drug prescribed in a Primary Care Area of Spain during study period.

METHOD

Illnesses and treatments registered in the Primary Care computerised medical history of patients were analysed during a 12month study period (2012). The original Beers criteria and their Spanish adaptation were used to evaluate PIM, considering both sets of criteria overall, and individually.

RESULTS

The median age of the patients was 76.0years, with the majority females (56.6%). Patients received a median of 13 active substances and 66 medical prescriptions. The percentage of patients prescribed PIM ranged from 44.8% according to the original Beers criteria to 49.4% with the Spanish adaptation.

CONCLUSIONS

PIMs are frequent in our context. The original Beers criteria, if not adapted to the local drug catalogue, underestimated the frequency of PIM in the elderly population studied.

摘要

目的

比较使用原始的《Beers标准》(评估老年人处方的全球参考标准)及其西班牙语版本检测潜在不适当用药(PIM)的情况。

设计

回顾性观察研究

地点

西班牙穆尔西亚省的一个初级保健区域

参与者

共有7856名65岁及以上的受试者,在研究期间至少在西班牙的一个初级保健区域开具过一种药物处方。

方法

在为期12个月的研究期间(2012年),分析患者初级保健计算机化病历中记录的疾病和治疗情况。使用原始的《Beers标准》及其西班牙语改编版来评估PIM,同时考虑这两套标准的整体情况和个别情况。

结果

患者的中位年龄为76.0岁,大多数为女性(56.6%)。患者接受的活性物质中位数为13种,医疗处方中位数为66张。根据原始的《Beers标准》,开具PIM的患者比例为44.8%,而西班牙语改编版为49.4%。

结论

在我们的研究背景下,PIM很常见。如果原始的《Beers标准》未根据当地药品目录进行调整,则会低估所研究老年人群中PIM的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d858/6836936/eb7d2b4217c9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d858/6836936/eb7d2b4217c9/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d858/6836936/eb7d2b4217c9/fx1.jpg

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