手术中局部应用 ALA-PDT 治疗上皮样血管肉瘤。
Treatment of Epithelioid angiosarcoma with Topical ALA-PDT in the course of surgery.
机构信息
Department of Plastic & Cosmetic Surgery, Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing 400042, PR China.
出版信息
Photodiagnosis Photodyn Ther. 2017 Sep;19:153-155. doi: 10.1016/j.pdpdt.2017.05.009. Epub 2017 May 12.
BACKGROUND
Epithelioid angiosarcoma is a high grade malignancy sarcoma of soft tissue, which is hard to diagnose and completely excise without causing functional and cosmetic problems. Moreover, the high rate of recurrence is hard to salvage. Photodynamic therapy is a novel treatment protocol which can selectively destroy tumor cell with good functional and cosmetic outcomes.
METHODS
This is a case about a 81 years old patient with Epithelioid angiosarcoma in the right medial angle of eye, which received surgery and ALA photodynamic therapy.
RESULTS
There is no recurrence in one year after treatment of surgery and photodynamic therapy in the course of surgery.
CONCLUSIONS
Excision combined with photodynamic therapy during operation is a promising strategy towards tumors which are hard to resect thoroughly and have a high risk of recurrence.
背景
上皮样血管肉瘤是一种软组织的高级别恶性肉瘤，在不引起功能和美容问题的情况下彻底切除非常困难。此外，高复发率难以挽救。光动力疗法是一种新的治疗方案，它可以选择性地破坏肿瘤细胞，同时获得良好的功能和美容效果。
方法
这是一例 81 岁患者，右侧内眼角患有上皮样血管肉瘤，接受了手术和 ALA 光动力疗法。
结果
在手术过程中进行手术和光动力疗法治疗后，一年后无复发。
结论
对于难以彻底切除且复发风险高的肿瘤，切除联合术中光动力治疗是一种很有前途的策略。
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