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男男性行为者中具有临床意义的抑郁症状和性行为

Clinically significant depressive symptoms and sexual behaviour among men who have sex with men.

作者信息

Miltz Ada R, Rodger Alison J, Sewell Janey, Speakman Andrew, Phillips Andrew N, Sherr Lorraine, Gilson Richard J, Asboe David, Nwokolo Nneka C, Clarke Amanda, Gompels Mark M, Allan Sris, Collins Simon, Lampe Fiona C

机构信息

, MSc, HIV Epidemiology and Biostatistics Group, Research Department of Infection and Population Health, University College London, London, UK.

, MD, HIV Epidemiology and Biostatistics Group, Research Department of Infection and Population Health, University College London, London, UK.

出版信息

BJPsych Open. 2017 May 8;3(3):127-137. doi: 10.1192/bjpo.bp.116.003574. eCollection 2017 May.

Abstract

BACKGROUND

The relationship between depression and sexual behaviour among men who have sex with men (MSM) is poorly understood.

AIMS

To investigate prevalence and correlates of depressive symptoms (Patient Health Questionnaire-9 score ≥10) and the relationship between depressive symptoms and sexual behaviour among MSM reporting recent sex.

METHOD

The Attitudes to and Understanding of Risk of Acquisition of HIV (AURAH) is a cross-sectional study of UK genitourinary medicine clinic attendees without diagnosed HIV (2013-2014).

RESULTS

Among 1340 MSM, depressive symptoms (12.4%) were strongly associated with socioeconomic disadvantage and lower supportive network. Adjusted for key sociodemographic factors, depressive symptoms were associated with measures of condomless sex partners in the past 3 months (≥2 (prevalence ratio (PR) 1.42, 95% CI 1.17-1.74; =0.001), unknown or HIV-positive status (PR 1.43, 95% CI 1.20-1.71; <0.001)), sexually transmitted infection (STI) diagnosis (PR 1.46, 95% CI 1.19-1.79; <0.001) and post-exposure prophylaxis use in the past year (PR 1.83, 95% CI 1.33-2.50; <0.001).

CONCLUSIONS

Management of mental health may play a role in HIV and STI prevention.

DECLARATION OF INTEREST

A.N.P. has received payments for presentations made at meetings sponsored by Gilead in spring 2015. N.C.N. has received support for attendance at conferences, speaker fees and payments for attendance at advisory boards from Gilead Sciences, Viiv Healthcare, Janssen Pharmaceuticals and Bristol-Myers Squibb and a research grant from Gilead Sciences. D.A. served on the advisory board for Gilead in January 2016. M.M.G. has had sponsorship to attend conferences by Bristol-Myers Squibb, been on the BioCryst advisory board and run trials for Merck, Gilead, SSAT, BioCryst and Novartis.

COPYRIGHT AND USAGE

© The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.

摘要

背景

男男性行为者(MSM)中抑郁症与性行为之间的关系尚不清楚。

目的

调查抑郁症状(患者健康问卷-9得分≥10)的患病率及其相关因素,以及近期有性行为的男男性行为者中抑郁症状与性行为之间的关系。

方法

对艾滋病毒感染风险的态度与理解(AURAH)研究是一项针对英国未确诊艾滋病毒的泌尿生殖医学门诊患者的横断面研究(2013 - 2014年)。

结果

在1340名男男性行为者中,抑郁症状(12.4%)与社会经济劣势和较低的支持网络密切相关。在对关键社会人口学因素进行调整后,抑郁症状与过去3个月内无保护性行为的性伴侣数量(≥2个(患病率比(PR)1.42,95%置信区间1.17 - 1.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/959f/5421094/c41cb674185a/bjporcpsych003574-g001.jpg

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