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儿童颅咽管瘤手术干预后发生的内分泌紊乱

Endocrine Disorders Developing after Surgical Intervention of Craniopharyngioma in Children.

作者信息

Shohdy Kyrillus S, Rashad Wegdan

机构信息

Clinical Oncology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

Child Psychiatry Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Pediatr Endocrinol Rev. 2017 Mar;14(3):298-301.

Abstract

Craniopharyngiomas, albeit their benign nature, can cause severe damage to visual, hypothalamic, endocrine and neurologic functions which make their total resection an inevitable approach to save the patient's life. However, significant therapy-related long term complications make those traditional treatment options debatable and hazardous. This review will focus on the various complications that affect the childrens' quality of life considerably such as, diabetes insipidus, precocious puberty and hypothalamic obesity.

摘要

颅咽管瘤尽管本质上是良性的,但可对视神经、下丘脑、内分泌及神经功能造成严重损害,这使得全切除成为挽救患者生命的必然手段。然而,与治疗相关的严重长期并发症使这些传统治疗方案存在争议且具有危险性。本综述将聚焦于显著影响儿童生活质量的各种并发症,如尿崩症、性早熟和下丘脑性肥胖。

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