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中国武汉接受抗逆转录病毒治疗的艾滋病毒/艾滋病感染者抑郁症状的患病率及危险因素:简短报告

Prevalence of and risk factors for depressive symptoms among people living with HIV/AIDS receiving antiretroviral treatment in Wuhan, China: a short report.

作者信息

Rong Hu, Nianhua Xie, Jun Xu, Lianguo Ruan, Si Wu, Sheng Wei, Heng Guo, Xia Wang

机构信息

a Department of HIV/AIDS Prevention , Wuhan Centers for Disease Prevention and Control , Wuhan , China.

b Department of Infectious Diseases Treatment , Wuhan Medical Treatment Center , Wuhan , China.

出版信息

AIDS Care. 2017 Dec;29(12):1524-1528. doi: 10.1080/09540121.2017.1327649. Epub 2017 May 16.

Abstract

We aimed to explore the prevalence of and risk factors for depressive symptoms (DS) among people living with HIV/AIDS (PLWHA) receiving antiretroviral treatment (ART) in Wuhan, Hubei, China. A cross-sectional study evaluating adult PLWHA receiving ART in nine designated clinical hospitals was conducted from October to December 2015. The validated Beck Depression Inventory (BDI) was used to assess DS in eligible participants. Socio-demographical, epidemiological and clinical data were directly extracted from the case reporting database of the China HIV/AIDS Information Network. Multinomial regression analysis was used to explore the risk factors for DS. 394 participants were finally included in all analyses. 40.3% were found to have DS with 13.7% having mild DS and 26.6% having moderate to severe DS. The results of multinomial regression analysis suggested that being married or living with a partner, recent experience of ART-related side effects, and/or history of HCV infection were positively associated with mild DS, while increasing age was positively associated with moderate to severe DS.

摘要

我们旨在探讨中国湖北省武汉市接受抗逆转录病毒治疗(ART)的艾滋病毒/艾滋病感染者(PLWHA)中抑郁症状(DS)的患病率及危险因素。2015年10月至12月,我们开展了一项横断面研究,评估了九家指定临床医院中接受ART的成年PLWHA。采用经过验证的贝克抑郁量表(BDI)对符合条件的参与者进行DS评估。社会人口统计学、流行病学和临床数据直接从中国艾滋病毒/艾滋病信息网络的病例报告数据库中提取。采用多项回归分析来探究DS的危险因素。最终,394名参与者纳入了所有分析。结果发现,40.3%的人有DS,其中13.7%为轻度DS,26.6%为中度至重度DS。多项回归分析结果表明,已婚或有伴侣、近期有ART相关副作用经历和/或丙型肝炎病毒(HCV)感染史与轻度DS呈正相关,而年龄增长与中度至重度DS呈正相关。

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