Wang Honghong, Zhang Caihong, Ruan Ye, Li Xianhong, Fennie Kristopher, Williams Ann B
J Assoc Nurses AIDS Care. 2014 Nov-Dec;25(6):568-76. doi: 10.1016/j.jana.2014.02.001. Epub 2014 Apr 13.
Depressive symptoms are common among people living with HIV (PLWH) and are associated with poor adherence to antiretroviral treatment and poor treatment outcomes. Our study investigated the prevalence of and factors associated with depressive symptoms in PLWH in one Chinese province. Data were collected from 496 PLWH between July 2009 and July 2010 at two HIV treatment sites in Hunan Province, China. Sixty-two percent (n = 309) of participants scored 16 or more on the Center for Epidemiological Studies of Depression scale, indicating moderate to high levels of depressive symptoms. Independent predictors of depressive symptoms included active heroin use, lack of a stable job, female gender, and limited social support. These data suggest that interventions addressing depressive symptoms should be included in HIV care programs provided by the Chinese government, with a special focus on PLWH who are heroin users, female, unemployed, or socially isolated.
抑郁症状在艾滋病毒感染者（PLWH）中很常见，并且与抗逆转录病毒治疗的依从性差和治疗效果不佳有关。我们的研究调查了中国一个省份艾滋病毒感染者中抑郁症状的患病率及其相关因素。2009年7月至2010年7月期间，在中国湖南省的两个艾滋病毒治疗点收集了496名艾滋病毒感染者的数据。62%（n = 309）的参与者在流行病学研究中心抑郁量表上的得分达到或超过16分，表明存在中度至高度的抑郁症状。抑郁症状的独立预测因素包括当前使用海洛因、缺乏稳定工作、女性性别以及社会支持有限。这些数据表明，中国政府提供的艾滋病毒护理项目应纳入针对抑郁症状的干预措施，特别关注那些使用海洛因、女性、失业或社会孤立的艾滋病毒感染者。
