Nishina Makoto, Yanagi Hidetaka, Koizumi Masahiro, Kimura Moritsugu, Kakuta Takatoshi, Endoh Masayuki, Fukagawa Masafumi, Takagi Atsushi
Division of General Internal Medicine, Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Division of Nephrology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
CEN Case Rep. 2012 Nov;1(2):73-76. doi: 10.1007/s13730-012-0016-3. Epub 2012 Jun 6.
Pasteurella multocida (P. multocida) is an aerobic Gram-negative coccobacillus, which is found as part of the natural oral flora of many animals, including most healthy cats and dogs. However, it can cause a variety of infections in humans, usually as a result of the patient being bitten or scratched by a cat or dog. There have been 22 reported cases of P. multocida peritonitis in patients undergoing peritoneal dialysis (PD). Of these, 66.7 % occurred within 12 months of the initiation of PD. Only two cases (11.1 %) developed more than 60 months after the commencement of PD. We report a case of P. multocida peritonitis involving a 45-year-old patient who had been undergoing continuous ambulatory peritoneal dialysis (CAPD) for 84 months without a previous history of peritonitis, who developed P. multocida peritonitis associated with a domestic cat on the very night on which he began using an automated cycler device to switch from CAPD to continuous cyclic peritoneal dialysis (CCPD). Patients maintained on PD who keep pets such as cats or dogs at home should be educated about the risk of developing peritonitis related to their domestic pets, and this warning should be repeated when such patients switch from CAPD to CCPD. Physicians should consider using empiric therapy to prevent P. multocida in pet-owning PD patients who present with a history of PD fluid leakage and peritonitis, especially in patients who use cycler devices.
多杀巴斯德菌是一种需氧革兰氏阴性球杆菌,作为许多动物自然口腔菌群的一部分存在,包括大多数健康的猫和狗。然而,它可在人类中引起多种感染,通常是由于患者被猫或狗咬伤或抓伤所致。在接受腹膜透析(PD)的患者中,已有22例多杀巴斯德菌腹膜炎的报道。其中,66.7%发生在开始PD的12个月内。只有2例(11.1%)在PD开始60多个月后发病。我们报告一例多杀巴斯德菌腹膜炎病例,患者为一名45岁男性,他已持续非卧床腹膜透析(CAPD)84个月,此前无腹膜炎病史,在开始使用自动循环装置从CAPD转为持续循环腹膜透析(CCPD)的当晚,发生了与家猫相关的多杀巴斯德菌腹膜炎。对于在家中饲养猫或狗等宠物的PD患者,应告知他们发生与家养宠物相关腹膜炎的风险,并且当此类患者从CAPD转为CCPD时,应再次进行此警告。对于有腹膜透析液渗漏和腹膜炎病史的养宠物的腹膜透析患者,尤其是使用循环装置的患者,医生应考虑使用经验性治疗来预防多杀巴斯德菌感染。