Fayaz Mohamed Salah, Al-Qaderi Aishah Ebrahim, El-Sherify Mustafa Shawki
Kuwait Cancer Control Center, Shuwaikh, Kuwait City, Kuwait.
CEN Case Rep. 2017 May;6(1):36-38. doi: 10.1007/s13730-016-0239-9. Epub 2016 Oct 26.
Renal cell carcinoma has the ability to metastasize to any organ; about 16 % of affected patients present initially with metastasis. However, it is rare for this tumor to present with metastasis from an unidentified primary. The current use of immunohistochemistry and molecular genetics has enabled clinicians to reach a precise diagnosis. It has been hypothesized that the treatment protocol for metastatic renal cell carcinoma can be applied to cases with undetectable primary. In this paper, a novel case of metastatic renal cell carcinoma presenting with lymphadenopathy with no evidence of a primary renal lesion is reported from Kuwait cancer center.
肾细胞癌有转移至任何器官的能力；约16%的患者初诊时即有转移。然而，该肿瘤以不明原发灶转移的情况较为罕见。目前免疫组化和分子遗传学的应用使临床医生能够做出准确诊断。据推测，转移性肾细胞癌的治疗方案可应用于未检测到原发灶的病例。本文报道了科威特癌症中心的一例新型转移性肾细胞癌病例，该病例表现为淋巴结病且无原发性肾病变证据。
